Evidence map›Paper›PMID 38960982›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2024

Race-specific FRAX models are evidence-based and support equitable care: a response to the ASBMR Task Force report on Clinical Algorithms for Fracture Risk.

John A Kanis, Nicholas C Harvey, Mattias Lorentzon, Enwu Liu, Marian Schini, Bo Abrahamsen, Jonathan D Adachi, Majed Alokail, Fredrik Borgstrom, Olivier Bruyère and 27 more

Abstract read
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In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Revised Swedish FRAX models and the establishment of age-dependent intervention thresholds.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  8. Changes in treatment eligibility with race-neutral US FRAX would be modest: estimates using the National Health and Nutrition Examination Survey (NHANES).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  9. Article
  10. Article
  11. The association of bone density and hip fracture risk among Asian women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

John A KanisMary McKillop Institute for Health Research, Catholic University, AustralianMelbourne, Australia. w.j.pontefract@shef.ac.uk.ORCID http://orcid.org/0000-0002-3129-4326
Nicholas C HarveyMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Mattias LorentzonMary McKillop Institute for Health Research, Catholic University, AustralianMelbourne, Australia.
Enwu LiuMary McKillop Institute for Health Research, Catholic University, AustralianMelbourne, Australia.
Marian SchiniDivision of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK.
Bo AbrahamsenOdense Patient Data Explorative Network, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.
Jonathan D AdachiDepartment of Medicine, McMaster University, Hamilton, Canada.
Majed AlokailBiochemistry Department, College of Science, Riyadh, Kingdom of Saudi Arabia.
Fredrik BorgstromQuantify Research, Stockholm, Sweden.
Olivier BruyèreResearch Unit in Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
John J CareySchool of Medicine, University of Galway, Galway, Ireland.ORCID http://orcid.org/0000-0001-7292-2328
Patricia ClarkClinical Epidemiology Research Unit, Hospital Infantil de Mexico "Federico Gomez", Mexico City, Mexico.
Cyrus CooperMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Elizabeth M CurtisMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0002-5147-0550
Elaine M DennisonMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Manuel Díaz-CurielMetabolic Bone Diseases Unit, Department of Internal Medicine, Hospital Universitario Fundación Jiménez Díaz, Universidad Autónoma Madrid, Madrid, Spain.
Hans P DimaiDepartment of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Styria, Austria.
Daniel GrigorieCarol Davila University of Medicine, Bucharest, Romania.
Mickael HiligsmannDepartment of Health Services Research, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
Patricia KhashayarInternational Institute for Biosensing, University of Minnesota, Minneapolis, USA.
Willem LemsDepartment of Rheumatology, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands.
E Michael LewieckiNew Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, USA.
Roman S LorencMultidisciplinary Osteoporosis Forum, Warsaw, Poland, Poland.
Alexandra PapaioannouMcMaster University, Hamilton, ON, Canada.
Jean-Yves ReginsterProtein Research Chair, Biochemistry Dept, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID http://orcid.org/0000-0001-6290-752X
René RizzoliDivision of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
Eric ShiromaLaboratory of Epidemiology and Population Sciences, National Institute On Aging, Baltimore, MD, USA.
Stuart L SilvermanDepartment of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Eleanor SimonsickTranslational Gerontology Branch, National Institute On Aging Intramural Research Program, Baltimore, MD, USA.
Manuel Sosa-HenríquezUniversity of Las Palmas de Gran Canaria, Grand Canaries, Spain.
Pawel SzulcINSERM UMR 1033, University of Lyon, Hospital Edouard Herriot, Lyon, France.
Kate A WardMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0001-7034-6750
Noriko YoshimuraDepartment of Preventive Medicine for Locomotive Organ Disorders, The University of Tokyo Hospital, Tokyo, Japan.
Helena JohanssonMary McKillop Institute for Health Research, Catholic University, AustralianMelbourne, Australia.
Liesbeth VandenputMary McKillop Institute for Health Research, Catholic University, AustralianMelbourne, Australia.ORCID http://orcid.org/0000-0002-1712-6131
Eugene V McCloskeyCentre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0003-0177-8140
Board of IOF, and the IOF Working Group on Epidemiology and Quality of Life

Funding

Medical Research Council MC_PC_21003Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/2
6 · The paper itself

Abstract

Task Force on 'Clinical Algorithms for Fracture Risk' commissioned by the American Society for Bone and Mineral Research (ASBMR) Professional Practice Committee has recommended that FRAX® models in the US do not include adjustment for race and ethnicity. This position paper finds that an agnostic model would unfairly discriminate against the Black, Asian and Hispanic communities and recommends the retention of ethnic and race-specific FRAX models for the US, preferably with updated data on fracture and death hazards. In contrast, the use of intervention thresholds based on a fixed bone mineral density unfairly discriminates against the Black, Asian and Hispanic communities in the US. This position of the Working Group on Epidemiology and Quality of Life of the International Osteoporosis Foundation (IOF) is endorsed both by the IOF and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).

Indexed as

AlgorithmsBone DensityEvidence-Based MedicineOsteoporotic FracturesFemaleHumansOsteoporosisRisk AssessmentUnited StatesFracture probabilityFRAX adjustmentRace and ethnicityRacism

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.