Evidence map›Paper›PMID 38960964›Full record

ArticleBulletin of experimental biology and medicine2024

Comparative Morphological and Molecular Genetic Characteristics of Cell and Tissue Strains of Experimental Rat Glioma 10-17-2 (Astrid-17).

A I Alekseeva, V V Kudelkina, A S Khalansky, A V Sentyabreva, E A Miroshnichenko, M V Gulyaev, K A Rakitina, A M Kosyreva

Abstract readComparative Study
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

A I AlekseevaAvtsyn Research Institute of Human Morphology, Petrovsky Russian Research Center of Surgery, Moscow, Russia. mariott@bk.ru.
V V KudelkinaAvtsyn Research Institute of Human Morphology, Petrovsky Russian Research Center of Surgery, Moscow, Russia.
A S KhalanskyAvtsyn Research Institute of Human Morphology, Petrovsky Russian Research Center of Surgery, Moscow, Russia.
A V SentyabrevaAvtsyn Research Institute of Human Morphology, Petrovsky Russian Research Center of Surgery, Moscow, Russia.
E A MiroshnichenkoAvtsyn Research Institute of Human Morphology, Petrovsky Russian Research Center of Surgery, Moscow, Russia.
M V GulyaevFaculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow, Russia.
K A RakitinaMedical Institute, RUDN University, Moscow, Russia.
A M KosyrevaAvtsyn Research Institute of Human Morphology, Petrovsky Russian Research Center of Surgery, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to obtain models of gliomas of varying degrees of malignancy, we performed morphological and molecular genetic study of a tissue strain of glioma 10-17-2 (Astrid-17) obtained by intracranial passaging of tumor fragments of chemically induced rat brain tumor, and a cell strain isolated from it. More or less pronounced changes in the expression levels of Mki67, Trp53, Vegfa, and Gfap genes in the tissue and cell strain of glioma 10-17-2 (Astrid-17) compared with intact brain tissue were shown. The tissue model of glioma 10-17-2 (Astrid-17) according to the studied characteristics shows features of grade 3-4 astrocytoma and the cellular model - grade 2-3 astrocytoma.

Indexed as

Brain NeoplasmsGlial Fibrillary Acidic ProteinGliomaVascular Endothelial Growth Factor AAnimalsAstrocytomaBrainCell Line, TumorGene Expression Regulation, NeoplasticKi-67 AntigenMaleRatsTumor Suppressor Protein p53Gfap protein, ratGlial Fibrillary Acidic ProteinKi-67 AntigenTumor Suppressor Protein p53Vascular Endothelial Growth Factor Avascular endothelial growth factor A, ratAstrid-17astrocytomaastrogliagliomaproliferation

Identifiers

PMID38960964

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.