Evidence map›Paper›PMID 38960962›Full record

ArticleBulletin of experimental biology and medicine2024

Analysis of the Diversity and Functional Potential of Bacterial Communities in Tuberculomas.

E A Orlova, O B Ogarkov, I G Kondratov, V V Sinkov, N L Belkova, A E Suzdalnitsky, S V Kirilchik, A V Nebesnykh, L I Kolesnikova

Abstract read
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Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Metagenomic Analysis of Caseum of Tuberculosis Foci.Bulletin of experimental biology and medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

E A OrlovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia. elizaveta.a.orlova@gmail.com.
O B OgarkovScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
I G KondratovScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
V V SinkovScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
N L BelkovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
A E SuzdalnitskyIrkutsk Regional Clinical Tuberculosis Hospital, Irkutsk, Russia.
S V KirilchikIrkutsk Regional Cancer Center, Irkutsk, Russia.
A V NebesnykhIrkutsk Regional Cancer Center, Irkutsk, Russia.
L I KolesnikovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamics of lung microbiota in tuberculosis remains poorly understood. Sequencing of variable regions of the 16S rRNA gene from surgically excised tuberculosis foci and biopsy specimens of normal lung tissue allowed characterization of the diversity and predictive potential of bacterial communities. Taxonomic diversity indices attested to differences in the structure of microbial communities between "healthy" lungs and tuberculomas. The microbial composition of "healthy" lungs varied in taxonomic diversity and was presented by both gram-positive and gram-negative bacteria with sufficiently similar metabolic potential. The microbiota of the examined tuberculomas consisted of Mycobacterium tuberculosis in 99.9% of cases. A significant part of the metabolic pathways predicted by PICRUSt2 included cholesterol catabolism, sulfate assimilation, and various pathways for the biosynthesis of cell wall components.

Indexed as

LungMycobacterium tuberculosisRNA, Ribosomal, 16STuberculomaAdultFemaleGram-Negative BacteriaGram-Positive BacteriaHumansMaleMicrobiotaMiddle AgedTuberculosis, PulmonaryRNA, Ribosomal, 16S16S rRNA genelungsmicrobiotaPICRUSttuberculoma

Identifiers

PMID38960962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.