Evidence map›Paper›PMID 38960719›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Human Cervical Epidural Spinal Electrogram Topographically Maps Distinct Volitional Movements.

Poojan D Shukla, John F Burke, Nikhita Kunwar, Kara Presbrey, Jannine Balakid, Maria Yaroshinsky, Kenneth Louie, Line Jacques, Prasad Shirvalkar, Doris D Wang

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In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Poojan D ShuklaDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California 94143.
John F BurkeDepartment of Neurosurgery, University of Oklahoma, Oklahoma City, Oklahoma 73104.
Nikhita KunwarSchool of Medicine, University of California San Diego, San Diego, California 92093.
Kara PresbreyDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California 94143.
Jannine BalakidDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California 94143.
Maria YaroshinskyDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California 94143.
Kenneth LouieDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California 94143.ORCID 0000-0003-1702-1521
Line JacquesDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California 94143.
Prasad ShirvalkarDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California 94143.
Doris D WangDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California 94143 doris.wang@ucsf.edu.ORCID 0000-0001-6112-3002

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Little is known about the electrophysiologic activity of the intact human spinal cord during volitional movement. We analyzed epidural spinal recordings from a total of five human subjects of both sexes during a variety of upper extremity movements and found that these spinal epidural electrograms contain spectral information distinguishing periods of movement, rest, and sensation. Cervical epidural electrograms also contained spectral changes time-locked with movement. We found that these changes were primarily associated with increased power in the theta (4-8 Hz) band and feature increased theta phase to gamma amplitude coupling, and this increase in theta power can be used to topographically map distinct upper extremity movements onto the cervical spinal cord in accordance with established myotome maps of the upper extremity. Our findings have implications for the development of neurostimulation protocols and devices focused on motor rehabilitation for the upper extremity, and the approach presented here may facilitate spatiotemporal mapping of naturalistic movements.

Indexed as

MovementAdultCervical CordCervical VertebraeElectromyographyEpidural SpaceFemaleHumansMaleMiddle AgedVolitionepidural spinal recordingspinal cordspinal electrophysiologyspinal mappingspinetuning curve

Identifiers

PMID38960719
PMCPMC11308355

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.