Evidence map›Paper›PMID 38960683›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Complete Match of Streptococcus salivarius from Oral Saliva and Stool in a Patient with Hepatic Encephalopathy.

Nao Nomura, Akira Také, Haruki Uojima, Yoshihiko Sakaguchi, Kazuyoshi Gotoh, Takashi Satoh, Hisashi Hidaka, Kazue Horio, Masashi Mizokami, Shunji Hayashi and 1 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nao NomuraDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Akira TakéDepartment of Microbiology, Kitasato University School of Medicine, Japan.
Haruki UojimaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Yoshihiko SakaguchiDepartment of Microbiology, Kitasato University School of Medicine, Japan.
Kazuyoshi GotohDepartment of Bacteriology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan.
Takashi SatohDivision of Hematology, Kitasato University School of Allied Health Sciences, Japan.
Hisashi HidakaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Kazue HorioDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
Masashi MizokamiDepartment of Genome Medical Sciences Project, Research Institute, National Center for Global Health and Medicine, Japan.
Shunji HayashiDepartment of Microbiology, Kitasato University School of Medicine, Japan.
Chika KusanoDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a 67-year-old Japanese woman with liver cirrhosis caused by primary biliary cholangitis. The patient was admitted to the hospital with loss of consciousness. Hepatic encephalopathy (HE) was diagnosed after diagnostic imaging and symptom assessments. Molecular biology tests were performed on oral saliva and stool samples. The test results indicated sequence similarity between urease-positive S. salivarius in both oral saliva and stool, as revealed by the signals in the overlapping peaks. This bacterium can potentially increase ammonia production in the gut, leading to HE in patients with liver cirrhosis.

Indexed as

FecesHepatic EncephalopathySalivaStreptococcal InfectionsStreptococcus salivariusAgedFemaleHumansLiver Cirrhosishepatic encephalopathyliver cirrhosisStreptococcus salivariusurease-activity

Identifiers

PMID38960683
PMCPMC11904461

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.