Evidence map›Paper›PMID 38960453›Full record

ArticleArchives of disease in childhood. Fetal and neonatal edition2024

Brain 3T magnetic resonance imaging in neonates: features and incidental findings from a research cohort enriched for preterm birth.

Gemma Sullivan, Alan J Quigley, Samantha Choi, Rory Teed, Manuel Blesa Cabez, Kadi Vaher, Amy Corrigan, David Q Stoye, Michael J Thrippleton, Mark Bastin and 1 more

Abstract read
In one paragraph

Article in Archives of disease in childhood. Fetal and neonatal edition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gemma SullivanThe University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK gemma.sullivan@ed.ac.uk.ORCID http://orcid.org/0000-0003-1499-3536
Alan J QuigleyRadiology, Royal Hospital for Children and Young People, Edinburgh, UK.
Samantha ChoiRadiology, Royal Hospital for Children and Young People, Edinburgh, UK.
Rory TeedThe University of Edinburgh MRC Centre for Reproductive Health, Edinburgh, UK.
Manuel Blesa CabezThe University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK.
Kadi VaherThe University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK.
Amy CorriganThe University of Edinburgh MRC Centre for Reproductive Health, Edinburgh, UK.
David Q StoyeThe University of Edinburgh MRC Centre for Reproductive Health, Edinburgh, UK.ORCID http://orcid.org/0000-0002-2444-3573
Michael J ThrippletonThe University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK.
Mark BastinThe University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK.
James P BoardmanThe University of Edinburgh Centre for Clinical Brain Sciences, Edinburgh, UK.ORCID http://orcid.org/0000-0003-3904-8960

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe survival rate and patterns of brain injury after very preterm birth are evolving with changes in clinical practices. Additionally, incidental findings can present legal, ethical and practical considerations. Here, we report MRI features and incidental findings from a large, contemporary research cohort of very preterm infants and term controls.

methods288 infants had 3T MRI at term-equivalent age: 187 infants born <32 weeks without major parenchymal lesions, and 101 term-born controls. T1-weighted, T2-weighted and susceptibility-weighted imaging were used to classify white and grey matter injury according to a structured system, and incidental findings described.

results

conclusionsOne-fifth of very preterm infants without major parenchymal lesions have white or grey matter abnormalities at term-equivalent age. Incidental findings are seen in 6% of preterm and 35% of term infants. Overall, 3% of infants undergoing MRI for research require follow-up due to incidental findings. These data should help inform consent procedures for research and assist service planning for centres using 3T neonatal brain MRI for clinical purposes.

Indexed as

Incidental FindingsMagnetic Resonance ImagingBrainBrain InjuriesCase-Control StudiesCohort StudiesFemaleGestational AgeHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesIntracranial HemorrhagesMaleWhite Mattermagnetic resonance imagingneonatologyneurology

Identifiers

PMID38960453
PMCPMC11672019

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.