Evidence map›Paper›PMID 38959032›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

NRF2 is a spatiotemporal metabolic hub essential for the polyfunctionality of Th2 cells.

Garam Choi, Hye-Yeon Ju, Jahyun Bok, Jungseo Choi, Jae Woo Shin, Hansol Oh, Yeojin Jeon, Jiyeon Kim, Daehong Kim, Heesu Moon and 7 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Control of T-cell immunity by fatty acid metabolism.Annals of pediatric endocrinology & metabolism · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Garam Choi *Laboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0003-1375-105X
Hye-Yeon Ju *Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.ORCID 0000-0002-3208-4611
Jahyun Bok *Laboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-8478-9472
Jungseo ChoiLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0009-0002-4432-9281
Jae Woo ShinLaboratory of Mucosal Immunology in Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Hansol OhLaboratory of Molecular Immunology, Department of Biological Science, Ulsan National Institute of Science & Technology, Ulsan 44919, Republic of Korea.ORCID 0009-0003-8362-1821
Yeojin JeonLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-6357-5395
Jiyeon KimLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0003-0537-838X
Daehong KimLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-5194-8414
Heesu MoonLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Jeong-Eun LeeLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Young-Sam KeumCollege of Pharmacy and Integrated Research, Institute for Drug Development, Dongguk University, Goyang 10326, Republic of Korea.ORCID 0000-0002-9348-466X
You-Me KimGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.ORCID 0000-0001-8780-704X
Hye Young KimLaboratory of Mucosal Immunology in Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0001-5978-512X
Sung Ho ParkLaboratory of Molecular Immunology, Department of Biological Science, Ulsan National Institute of Science & Technology, Ulsan 44919, Republic of Korea.ORCID 0000-0003-4856-7287
Mi-Ryung HanDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.ORCID 0000-0003-1745-6461
Yeonseok ChungLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-5780-4841

Funding

National Research Foundation of Korea (NRF) 201R1A6A3A01086970National Research Foundation of Korea (NRF) 2020R1A3B2078890National Research Foundation of Korea (NRF) 2022R1A6A1A03046247
6 · The paper itself

Abstract

Upon encountering allergens, CD4

Indexed as

AsthmaNF-E2-Related Factor 2Th2 CellsAnimalsCytokinesDisease Models, AnimalEosinophiliaFemaleGlycolysisHumansInterleukin-33LungMiceMice, Inbred C57BLMice, KnockoutOxidative PhosphorylationCytokinesInterleukin-33NFE2L2 protein, humanNfe2l2 protein, mouseNF-E2-Related Factor 2PPAR gammaPparg protein, mouseReactive Oxygen Speciesmetabolic fitnessNRF2OXPHOSPPARγTh2 cell

Identifiers

PMID38959032
PMCPMC11252815

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.