Evidence map›Paper›PMID 38958854›Full record

SynthesisSleep & breathing = Schlaf & Atmung2024

Genetics and sleep bruxism: a systematic review and meta-analysis of studies with twins.

Laiane Fernandes Pereira, Francisco Wilker Mustafa Gomes Muniz, Marina de Deus Moura de Lima, Cassiano Kuchenbecker Rösing, Lúcia de Fátima Almeida de Deus Moura, Marcoeli Silva de Moura, Cacilda Castelo Branco Lima

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Role of muscle-related genes in sleep bruxism : Understanding the genetic aspect of this behavior.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2025
    Article
  3. Oral health-related quality of life and factors associated with sleep bruxism in Brazilian preschool children: comparative cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laiane Fernandes PereiraPostgraduate Program in Dentistry, Federal University of Piaui, Teresina, Piaui, Brazil.ORCID 0000-0002-0495-2848
Francisco Wilker Mustafa Gomes MunizDepartment of Periodontology, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.ORCID 0000-0002-3945-1752
Marina de Deus Moura de LimaDepartment of Pathology and Dental Clinic, Federal University of Piaui, Campus Universitário Ministro Petrônio Portella, Bloco 5 - Postgraduate Program in Dentistry, Teresina, Piaui, 64049-550, Brazil.ORCID 0000-0002-7641-6331
Cassiano Kuchenbecker RösingDepartment of Periodontology, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brasil.ORCID 0000-0002-8499-5759
Lúcia de Fátima Almeida de Deus MouraDepartment of Pathology and Dental Clinic, Federal University of Piaui, Campus Universitário Ministro Petrônio Portella, Bloco 5 - Postgraduate Program in Dentistry, Teresina, Piaui, 64049-550, Brazil.ORCID 0000-0002-4112-1533
Marcoeli Silva de MouraDepartment of Pathology and Dental Clinic, Federal University of Piaui, Campus Universitário Ministro Petrônio Portella, Bloco 5 - Postgraduate Program in Dentistry, Teresina, Piaui, 64049-550, Brazil.ORCID 0000-0002-9044-9025
Cacilda Castelo Branco LimaDepartment of Pathology and Dental Clinic, Federal University of Piaui, Campus Universitário Ministro Petrônio Portella, Bloco 5 - Postgraduate Program in Dentistry, Teresina, Piaui, 64049-550, Brazil. cacildacb@hotmail.com.ORCID 0000-0002-2977-6035

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo systematically review the literature regarding the concordance of sleep bruxism (SB) between monozygotic (MZ) and dizygotic (DZ) twins.

methodsThe registration for this systematic review was accomplished in the International Prospective Register of Systematic Reviews (PROSPERO, No. CRD42021251751). As of July 2022, four databases were searched, including PubMed, Scopus, Embase, and Web of Science, as well as the grey literature in Google Scholar and OpenGrey. Observational studies evaluating SB in MZ and DZ twins of any age and sex were included. For the evaluation of the risk of bias, the Joanna Briggs checklist was utilized. The certainty of evidence was assessed via the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system. Pooled and subgroup meta-analyses were performed to estimate concordance of SB ​​between twins (p < 0.05).

resultsIn total, 3,155 records were identified. In the qualitative analysis, eleven studies were included; of these, seven were included in the meta-analysis. The majority of the articles exhibited a low risk of bias (63.6%). Greater SB concordance was observed between MZ twins than between DZ twins in the analysis of general concordance (OR = 1.47; 95% CI = 1.07-2.02) and also positive concordance (OR = 1.53; 95% CI = 1.29-1.81). Within the subgroup analyses, the significance of the findings remained only for the reported/self-reported SB regarding general concordance (OR = 1.44; 95% CI = 1.07-1.95) and positive concordance (OR = 1.55; 95% CI = 1.28-1.88). Low certainty of the evidence was observed for the general concordance analysis, while moderate certainty was observed for the positive concordance.

conclusionThere was a higher concordance of SB in MZ twins compared to DZ twins, indicating a possible genetic influence on the condition's occurrence.

Indexed as

Sleep BruxismTwins, DizygoticTwins, MonozygoticDiseases in TwinsHumansGeneticsHereditySleep bruxismTwinsTwin study

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.