Evidence map›Paper›PMID 38958851›Full record

SynthesisJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2024

Infective endocarditis associated with left atrial appendage occlusion device: a contemporary systematic review.

Alejandro Sanchez-Nadales, Muftawu Iddrisu, Roshan Wardak, Genesis M Arriola, Jose Baez-Escudero, Bo Xu

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alejandro Sanchez-NadalesDepartment of Cardiology, Department of Cardiovascular Disease, Cleveland Clinic Florida, Weston, Weston Campus, FL, 33324, USA.
Muftawu IddrisuDepartment of Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL, 60657, USA.
Roshan WardakDepartment of Internal Medicine, Cleveland Clinic Florida, 33321, Weston, FL, USA.
Genesis M ArriolaDepartment of Cardiology, Department of Cardiovascular Disease, Cleveland Clinic Florida, Weston, Weston Campus, FL, 33324, USA.
Jose Baez-EscuderoDepartment of Cardiac Pacing and Electrophysiology, Department of Cardiovascular Disease, Cleveland Clinic Florida, Weston Campus, Weston, FL, 33324, USA.
Bo XuSection of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, 44195, USA. xub@ccf.org.ORCID http://orcid.org/0000-0002-2985-7468

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundData are limited regarding infective endocarditis (IE) complicating left atrial appendage occlusion (LAAO) device procedures. This systematic review examines the etiology, diagnosis, and management of infective endocarditis (IE) following LAAO.

methodsA comprehensive search of six databases was performed between 2007 and 2022. In selecting studies, articles were included if they provided information about IE complicating LAAO, with relevant clinical and imaging details. Articles were excluded if they were editorials, study protocols, letters, or abstracts.

resultsWe identified seven cases of IE complicating LAAO published between 2007 and 2022, from the United States and Europe, highlighting the exceedingly rare reported incidence of the condition. Staphylococcus aureus is the predominant organism implicated in LAAO infections. Echocardiography is a key imaging modality for diagnosing LAAO IE. Both antibiotic therapy and surgical intervention in appropriate patients are important for managing LAAO device-related IE.

conclusionsThe limited data in the current literature regarding LAAO IE underscores the need for prospective clinical trials to establish evidence-based guidelines for infection prophylaxis, diagnosis, and management. Our findings emphasize the importance of vigilance for device-related infections, especially as the use of LAAO devices continues to grow worldwide.

Indexed as

Atrial AppendageAtrial FibrillationEndocarditisEndocarditis, BacterialHumansProsthesis-Related InfectionsSeptal Occluder DeviceStaphylococcal Infections18F-FDG-PET imagingAtrial fibrillationEchocardiographyInfective endocarditisLeft atrial appendage occlusion deviceMultimodality cardiovascular imaging

Identifiers

PMID38958851

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.