Evidence map›Paper›PMID 38958796›Full record

ArticleEJNMMI research2024

Preclinical evaluation of [

Jae Hun Ahn, Min Hwan Kim, Kyongkyu Lee, Keumrok Oh, Hyunwoo Lim, Hee Seup Kil, Soon Jeong Kwon, Jae Yong Choi, Dae Yoon Chi, Yong Jin Lee

Abstract read
In one paragraph

Article in EJNMMI research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jae Hun AhnDivision of Applied RI, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, 01812, Korea.ORCID http://orcid.org/0009-0001-3339-5825
Min Hwan KimResearch Institute of Radiopharmaceuticals, FutureChem Co., Ltd., Seoul, 04793, Korea.ORCID http://orcid.org/0000-0002-6226-8497
Kyongkyu LeeResearch Institute of Radiopharmaceuticals, FutureChem Co., Ltd., Seoul, 04793, Korea.ORCID http://orcid.org/0000-0002-0964-3817
Keumrok OhResearch Institute of Radiopharmaceuticals, FutureChem Co., Ltd., Seoul, 04793, Korea.ORCID http://orcid.org/0000-0003-2025-6276
Hyunwoo LimResearch Institute of Radiopharmaceuticals, FutureChem Co., Ltd., Seoul, 04793, Korea.ORCID http://orcid.org/0009-0008-4455-6306
Hee Seup KilResearch Institute of Radiopharmaceuticals, FutureChem Co., Ltd., Seoul, 04793, Korea.ORCID http://orcid.org/0000-0002-0701-9519
Soon Jeong KwonResearch Institute of Radiopharmaceuticals, FutureChem Co., Ltd., Seoul, 04793, Korea.ORCID http://orcid.org/0009-0003-7206-6658
Jae Yong ChoiDivision of Applied RI, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, 01812, Korea.ORCID http://orcid.org/0000-0003-1901-8238
Dae Yoon ChiResearch Institute of Radiopharmaceuticals, FutureChem Co., Ltd., Seoul, 04793, Korea. dychi001@gmail.com.ORCID http://orcid.org/0000-0002-9862-3286
Yong Jin LeeDivision of Applied RI, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, 01812, Korea. yjlee@kirams.re.kr.ORCID http://orcid.org/0000-0002-7140-354X

Funding

Korea Dementia Research Center HU20C0492
6 · The paper itself

Abstract

backgroundN-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (FP-CIT), the representative cocaine derivative used in dopamine transporter imaging, is a promising biomarker, as it reflects the severity of Parkinson's disease (PD).

resultsBiodistribution, metabolite and excretion analyses were performed in mice and PD models were induced in rats using 6-hydroxydopamine (6-OHDA). The targeting efficiency of [

conclusionsThis study fills the gap regarding insufficient preclinical studies on [

Indexed as

ADMEDopamine transporterFP-CITIoflupaneParkinson’s disease

Identifiers

PMID38958796
PMCPMC11222350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.