Evidence map›Paper›PMID 38958727›Full record

ArticleInternational urogynecology journal2024

How Intravesical Platelet-Rich Plasma Can Help Patients with Interstitial Cystitis/Bladder Pain Syndrome: A Comprehensive Scoping Review.

Ahmed Soliman, Mariam Adel, Mohamed A Elnagar, Saif Elsonbaty, Ahmed El Hefnawy

Abstract readScoping Review
PubMed Publisher
In one paragraph

Article in International urogynecology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmed SolimanFaculty of Medicine, Mansoura University, 6 Al Ashqar St., of El Gomhouria St, Mansoura, Egypt. ahmedsolimann9090@gmail.com.ORCID 0000-0003-3964-3778
Mariam AdelFaculty of Medicine, Mansoura University, 6 Al Ashqar St., of El Gomhouria St, Mansoura, Egypt.
Mohamed A ElnagarFaculty of Medicine, Mansoura University, 6 Al Ashqar St., of El Gomhouria St, Mansoura, Egypt.
Saif ElsonbatyFaculty of Medicine, Mansoura University, 6 Al Ashqar St., of El Gomhouria St, Mansoura, Egypt.
Ahmed El HefnawyResearch Department, Mansoura Research Team (MRT), Mansoura, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisInterstitial cystitis/bladder pain syndrome (IC/BPS) is a condition characterized by chronic inflammation that affects the bladder. The study was aimed at evaluating the effectiveness of intravesical platelet-rich plasma (PRP) injections in patients with IC/BPS.

methodsWe conducted a comprehensive search strategy to involve studies that investigate the efficacy of intravesical PRP injections or instillations over different time intervals. Various outcome measures were assessed, including pain scores, functional outcomes, urodynamic parameters, and surface expressions on the urothelium.

resultsOur search strategy revealed 1,125 studies. After screening, ten articles met the inclusion criteria. Intravesical PRP significantly reduced the visual analog scale (VAS) compared with baseline scores. Several clinical trials reported significant improvements in the global response rate (GRA), O'Leary-Sant Symptom (OSS) questionnaire, Interstitial Cystitis Symptom Index (ICSI), and Interstitial Cystitis Problem Index (ICPI). Urodynamic parameters such as maximum flow rate (Qmax) and post-voiding residual (PVR) showed significant improvements in some studies.

conclusionThe study concluded that intravesical PRP injections could be a promising effective treatment option for IC/BPS patients by their significant ability to reduce pain. However, improvement of urodynamic and functional outcomes is still not clear. Further large comparative trials are still warranted to assess the efficacy of PRP instillation.

Indexed as

Cystitis, InterstitialPlatelet-Rich PlasmaAdministration, IntravesicalFemaleHumansPain MeasurementTreatment OutcomeCystitisIC/BPSInterstitial cystitisPainful bladder syndromePlateletPlatelet-rich plasmaPRP

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.