Evidence map›Paper›PMID 38958242›Full record

ArticleBiochemistry2024

Regiochemical Analysis of the ProTide Activation Mechanism.

Kyle M Glockzin, Tamari Narindoshvili, Frank M Raushel

Abstract read
In one paragraph

Article in Biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kyle M GlockzinDepartment of Biochemistry & Biophysics, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0002-9469-3404
Tamari NarindoshviliDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Frank M RaushelDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0002-5918-3089

Funding

The Discovery of Novel Metabolic Pathways for the Biosynthesis and Degradation of Complex Carbohydrates within the Human Gut MicrobiomeR35GM139428 · NIGMS · TEXAS A&M UNIVERSITY · PI RAUSHEL, FRANK M. · 2021 to 2025
$2.8M
NIGMS NIH HHS R35 GM139428
6 · The paper itself

Abstract

ProTides are nucleotide analogues used for the treatment of specific viral infections. These compounds consist of a masked nucleotide that undergoes

Indexed as

Phosphoric AcidsAmidesAnhydridesAntiviral AgentsHydrolysisMagnetic Resonance SpectroscopyOxygen IsotopesProTidesStereoisomerismWaterAmidesAnhydridesAntiviral AgentsOxygen Isotopesphosphoramidic acidPhosphoric AcidsProTidesWater

Identifiers

PMID38958242
PMCPMC11256751

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.