ArticleHuman brain mapping2024
Dynamic properties in functional connectivity changes and striatal dopamine deficiency in Parkinson's disease.
Article in Human brain mapping, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Gastric-Selective Associations of Caudate Functional Connectivity with Gastrointestinal Rhythms in Parkinson's Disease: A Resting-State fMRI and Electrogastroenterography Study.Brain sciences · 2026Article
- Dopamine-related alterations in functional brain network dynamic reconfiguration in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- Dynamic functional connectivity is related to cognitive performance of prodromal Lewy body dementia.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Diagnosis and Management of Parkinson Disease in Individuals with Pre-Existing Mood Disorders.International journal of environmental research and public health · 2026Review
- Dynamic brain synergy uncovers functional neural coordination in Parkinson's disease under dopaminergic modulation.Journal of neuroengineering and rehabilitation · 2026Article
- Trends and challenges in imaging research of Parkinson's disease: a 10-year bibliometric analysis.Psychoradiology · 2026Article
- Shared and distinct dynamic brain activity and functional connectivity variability in patients with isolated craniocervical dystonia.Brain communications · 2026Article
- Physical activity and network attack tolerance preserve motor function in Parkinson's disease: A pilot study.NPJ Parkinson's disease · 2025Article
- AI-assisted MRI segmentation analysis of brain region volume alterations in Parkinson's disease.Frontiers in human neuroscience · 2025Article
- Dynamic properties in functional connectivity changes and striatal dopamine deficiency in Parkinson's disease.Human brain mapping · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Recent studies in Parkinson's disease (PD) patients reported disruptions in dynamic functional connectivity (dFC, i.e., a characterization of spontaneous fluctuations in functional connectivity over time). Here, we assessed whether the integrity of striatal dopamine terminals directly modulates dFC metrics in two separate PD cohorts, indexing dopamine-related changes in large-scale brain network dynamics and its implications in clinical features. We pooled data from two disease-control cohorts reflecting early PD. From the Parkinson's Progression Marker Initiative (PPMI) cohort, resting-state functional magnetic resonance imaging (rsfMRI) and dopamine transporter (DaT) single-photon emission computed tomography (SPECT) were available for 63 PD patients and 16 age- and sex-matched healthy controls. From the clinical research group 219 (KFO) cohort, rsfMRI imaging was available for 52 PD patients and 17 age- and sex-matched healthy controls. A subset of 41 PD patients and 13 healthy control subjects additionally underwent
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.