Evidence map›Paper›PMID 38958130›Full record

ArticleJournal of the American Heart Association2024

Impaired Cardiac Sympathetic Activity Is Associated With Myocardial Remodeling and Established Biomarkers of Heart Failure.

Luis M da Silva, Andréa Coy-Canguçu, Layde R Paim, Adriana A Bau, Camila Nicolela Geraldo Martins, Stephan Pinheiro, Vinicius Citeli Ribeiro, Walter E Magalhães Rocha, Jose R Mattos-Souza, Roberto Schreiber and 7 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Luis M da SilvaFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0002-8816-8830
Andréa Coy-CanguçuFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0002-4161-8099
Layde R PaimFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0001-7596-6668
Adriana A BauFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0002-7010-3932
Camila Nicolela Geraldo MartinsFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0002-7696-4522
Stephan PinheiroFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0002-5792-6598
Vinicius Citeli RibeiroFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.
Walter E Magalhães RochaFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0002-6996-2035
Jose R Mattos-SouzaFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.
Roberto SchreiberFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0002-8930-7556
Lígia Antunes-CorreaFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0002-5639-1325
Andrei SpositoFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0001-7127-2052
Wilson NadruzFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0002-0003-5102
Celso D RamosFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0002-1312-1026
Tomas NeilanCardiovascular Imaging Research Center, Division of Cardiology and Department of Radiology, Massachusetts General Hospital Harvard Medical School Boston MA USA.ORCID 0000-0002-1513-8833
Michael Jerosch-HeroldNon-Invasive Cardiovascular Imaging Program, Department of Radiology Brigham and Women's Hospital and Harvard Medical School Boston MA USA.ORCID 0000-0001-9018-6731
Otávio R Coelho-FilhoFaculdade de Ciências Médicas Universidade Estadual de Campinas São Paulo Brazil.ORCID 0000-0003-4428-5186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMETHODS AND

resultsProspectively enrolled patients with HF (New York Heart Association class II-III) were stratified into HF with preserved left ventricular ejection fraction [LVEF] ≥45%) and reduced LVEF. Ventricular morphology/function and myocardial extracellular volume (ECV) fraction were quantified by cardiovascular magnetic resonance, global longitudinal strain by echocardiography, cardiac sympathetic function by heart-to-mediastinum ratio from

conclusionsAbnormally low cardiac sympathetic function in patients with HF with reduced and preserved LVEF is associated with extracellular volume expansion and decreased cardiopulmonary functional capacity.

Indexed as

BiomarkersHeart FailureStroke VolumeSympathetic Nervous SystemVentricular Remodeling3-IodobenzylguanidineAgedEchocardiographyExercise TestExercise ToleranceFemaleFibrosisHeartHumansMaleMiddle Aged3-IodobenzylguanidineBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Radiopharmaceuticalscardiac magnetic resonancecardiac sympathetic functionheart failureinterstitial fibrosis

Identifiers

PMID38958130
PMCPMC11292752

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.