Evidence map›Paper›PMID 38957957›Full record

ArticleACS chemical neuroscience2024

A Snake Venom Peptide and Its Derivatives Prevent Aβ

Luana Cristina Camargo, Ian Gering, Mohammadamin Mastalipour, Victoria Kraemer-Schulien, Tuyen Bujnicki, Dieter Willbold, Mônika A Coronado, Raphael J Eberle

Abstract read
In one paragraph

Article in ACS chemical neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luana Cristina CamargoInstitute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich 52428, Germany.ORCID 0000-0002-7223-037X
Ian GeringInstitute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich 52428, Germany.
Mohammadamin MastalipourFaculty of Mathematics and Natural Sciences, Institute of Physical Biology, Heinrich Heine University Düsseldorf, Düsseldorf 40225, Germany.
Victoria Kraemer-SchulienInstitute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich 52428, Germany.ORCID 0000-0002-7413-7646
Tuyen BujnickiInstitute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich 52428, Germany.
Dieter WillboldInstitute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich 52428, Germany.ORCID 0000-0002-0065-7366
Mônika A CoronadoInstitute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich 52428, Germany.ORCID 0000-0002-6518-6497
Raphael J EberleInstitute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich 52428, Germany.ORCID 0000-0002-8763-3884

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over a century has passed since Alois Alzheimer first described Alzheimer's disease (AD), and since then, researchers have made significant strides in understanding its pathology. One key feature of AD is the presence of amyloid-β (Aβ) peptides, which form amyloid plaques, and therefore, it is a primary target for treatment studies. Naturally occurring peptides have garnered attention for their potential pharmacological benefits, particularly in the central nervous system. In this study, nine peptide derivatives of Crotamine, a polypeptide from

Indexed as

Amyloid beta-PeptidesCrotalid VenomsPeptide FragmentsAnimalsCrotalusHumansPeptidesProtein AggregatesSnake VenomsAmyloid beta-Peptidesamyloid beta-protein (1-42)Crotalid VenomscrotaminePeptide FragmentsPeptidesProtein AggregatesSnake VenomsaggregationAβ42deaggregationd-peptidepeptidesnake venom

Identifiers

PMID38957957
PMCPMC11258689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.