Evidence map›Paper›PMID 38957727›Full record

ArticleDementia & neuropsychologia2024

Episodic memory improvement in illiterate adults attending late-life education irrespective of low socioeconomic status: insights from the PROAME study.

Emma Patrice Ruppert, João Victor de Faria Rocha, Aída Lourandes da Silva, Kelle Luisa Dos Santos Tomaz, Clarisse Vasconcelos Friedlaender, Joanna de Castro Magalhães Assenção, Luciana Paula Rincon, Norton Gray Ferreira Ribeiro, Dulce Constantina de Souza Santos, Ana Paula Zacarias Lima and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Dementia & neuropsychologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04473235 (Better Memory With Literacy Acquisition Later in Life), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04473235 nacompletednot on this map

Better Memory With Literacy Acquisition Later in Life

TypeinterventionalSponsorUniversity of California, San FranciscoRan2021 to 2022Enrolled108ConditionsMemory ImpairmentArmsLiteracy training, Non-Literacy training
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Emma Patrice RuppertFaculdade de Ciências Médicas de Minas Gerais, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0000-0001-5877-5472
João Victor de Faria RochaUniversidade Federal de Minas Gerais, Faculdade de Medicina, Grupo de Pesquisa Neurologia Cognitiva e do Comportamento, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0000-0002-6656-5405
Aída Lourandes da SilvaFaculdade de Ciências Médicas de Minas Gerais, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0000-0002-2777-7800
Kelle Luisa Dos Santos TomazUniversidade Federal de Minas Gerais, Faculdade de Medicina, Grupo de Pesquisa Neurologia Cognitiva e do Comportamento, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0009-0001-2757-3402
Clarisse Vasconcelos FriedlaenderUniversidade Federal de Minas Gerais, Faculdade de Medicina, Grupo de Pesquisa Neurologia Cognitiva e do Comportamento, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0000-0001-6170-371X
Joanna de Castro Magalhães AssençãoUniversidade Federal de Minas Gerais, Faculdade de Medicina, Grupo de Pesquisa Neurologia Cognitiva e do Comportamento, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0009-0009-4629-9662
Luciana Paula RinconUniversidade Federal de Minas Gerais, Faculdade de Medicina, Grupo de Pesquisa Neurologia Cognitiva e do Comportamento, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0009-0009-9725-8617
Norton Gray Ferreira RibeiroUniversidade Federal de Minas Gerais, Faculdade de Medicina, Grupo de Pesquisa Neurologia Cognitiva e do Comportamento, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0009-0003-3930-1943
Dulce Constantina de Souza SantosEscola Municipal Acadêmico Vivaldi, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0009-0003-4608-1571
Ana Paula Zacarias LimaEscola Municipal Dr. Júlio Soares, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0009-0007-2892-2591
Isabel Elaine AllenUniversity of California San Francisco, Global Brain Health Institute, San Francisco CA, USA.ORCID https://orcid.org/0000-0001-9029-9744
Paulo CaramelliUniversidade Federal de Minas Gerais, Faculdade de Medicina, Grupo de Pesquisa Neurologia Cognitiva e do Comportamento, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0000-0002-4786-6990
Lea Tenenholz GrinbergUniversity of California San Francisco, Global Brain Health Institute, San Francisco CA, USA.ORCID https://orcid.org/0000-0002-6809-0618
Francisca Izabel Pereira MacielUniversidade Federal de Minas Gerais, Faculdade de Medicina, Grupo de Pesquisa Neurologia Cognitiva e do Comportamento, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0000-0003-4751-2890
Elisa de Paula França ResendeFaculdade de Ciências Médicas de Minas Gerais, Belo Horizonte MG, Brazil.ORCID https://orcid.org/0000-0002-5730-1205

Funding

Research Education ComponentP30AG062422 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Serggio Carlo Lanata · 2019 to 2026
$36.9M
Clinical Features and Neuropathological Basis of Sleep Wake Behavior in Alzheimer's and PSPR01AG060477 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Lea Tenenholz Grinberg, Thomas C Neylan · 2019 to 2026
$8.2M
Better memory with literacy acquisition later in life: a randomized controlled trialR21AG069252 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRINBERG, LEA TENENHOLZ, RESENDE, ELISA · 2020 to 2021
$325k
NIA NIH HHS P30 AG062422NIA NIH HHS R01 AG060477NIA NIH HHS R21 AG069252
6 · The paper itself

Abstract

The majority of people with dementia live in low or middle-income countries (LMICs) where resources that play a crucial role in brain health, such as quality education, are still not widely available. In Brazil, illiteracy remains a prevalent issue, especially in communities with lower socioeconomic status (SES). The PROAME study set out to explore basic education in illiterate adults as a means to improve cognitive reserve. Objective: This manuscript aims to explore the relationship between SES and learning, as well as cognitive outcomes, in an older illiterate population. Methods: This six-month clinical trial (NCT04473235) involved 108 participants, of which 77 concluded all assessments, enrolled in late-life basic education. SES assessments included Quality of Urban Living Index, Municipal Human Development Index and Household SES calculated for each participant. Cognitive assessments encompassed the Free and Cued Selective Reminding Test (FCSRT), a word list to assess reading, and the Beta III matrix. Results: The sample consisted primarily of women, with a mean age of 58.5. Participants improved their reading (p=0.01) and their FCSRT (p=0.003). Regarding episodic memory, women outperformed men (p=0.007) and younger participants improved more than their older counterparts (p=0.001). There was no association observed between SES and cognitive outcomes. Conclusion: Irrespective of SES, participants demonstrated positive outcomes after attending basic education. These findings highlight that late life education could be an important non-pharmacologic preventative measure, especially in LMICs.

Indexed as

Cognitive AgingCognitive ReserveDementiaLiteracyMemory, EpisodicSocioeconomic Factors

Identifiers

PMID38957727
PMCPMC11218930

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.