Evidence map›Paper›PMID 38957553›Full record

ArticleAnnals of gastroenterological surgery2024

What is the crux of successful living-donor liver transplantation for recipients aged 70 and beyond?

Takeo Toshima, Shinji Itoh, Yoshihiro Nagao, Shohei Yoshiya, Yuki Bekki, Takuma Izumi, Norifumi Iseda, Yuriko Tsutsui, Katsuya Toshida, Tomoharu Yoshizumi

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takeo ToshimaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0003-4019-8288
Shinji ItohDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0003-0382-2520
Yoshihiro NagaoDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0003-4070-7329
Shohei YoshiyaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0003-4642-5058
Yuki BekkiDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Takuma IzumiDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Norifumi IsedaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Yuriko TsutsuiDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Katsuya ToshidaDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Tomoharu YoshizumiDepartment of Surgery and Science, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.ORCID https://orcid.org/0000-0002-4497-1816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: There is limited evidence regarding the feasibility of living-donor liver transplantation (LDLT) for patients aged over 70. The aims of this study were to assess postoperative outcomes in elderly recipients and to ascertain the potential feasibility and acceptability of LDLT. Methods: Data were collected from 762 recipients, including 26 in the elderly group (aged ≥70) and 736 in the younger group (aged <70), and reviewed even by propensity score matching (PSM). Results: No significant differences were observed in the frequency of postoperative complications between the two groups. Additionally, both groups exhibited a comparable 30-day mortality rate after LDLT (3.9% in both) and similar hospital stays (36 days vs. 40 days). The 1-, 3-, and 5-year graft survival rates in the elderly group were 92.0%, which was comparable to those in the younger group ( Conclusion: LDLT can be performed safely for elderly patients aged 70 years or older, provided they have a preserved PS and receive high-quality grafts from younger donors, inevitably all children of elderly recipients. This approach yields acceptable long-term outcomes. Consequently, age alone should not serve as an absolute contraindication for LDLT.

Indexed as

elderly patientindication for liver transplantationliver transplantationliving‐donor liver transplantationperformance status

Identifiers

PMID38957553
PMCPMC11216780

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.