Evidence map›Paper›PMID 38957404›Full record

ArticleMaterials advances2024

A one-step method for generating antimicrobial nanofibre meshes

Fangyuan Zhang, Amy I Jacobs, Maximillian Woodall, Helen C Hailes, Ijeoma F Uchegbu, Delmiro Fernandez-Reyes, Claire M Smith, Karolina Dziemidowicz, Gareth R Williams

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fangyuan ZhangUCL School of Pharmacy, University College London 29-39 Brunswick Square London WC1N 1AX UK k.dziemidowicz@ucl.ac.uk g.williams@ucl.ac.uk.
Amy I JacobsUCL Great Ormond Street Institute of Child Health, University College London 30 Guilford Street London WC1N 1EH UK.
Maximillian WoodallUCL Great Ormond Street Institute of Child Health, University College London 30 Guilford Street London WC1N 1EH UK.
Helen C HailesDepartment of Chemistry, University College London 20 Gordon Street London WC1H 0AJ UK.ORCID https://orcid.org/0000-0001-5574-4742
Ijeoma F UchegbuUCL School of Pharmacy, University College London 29-39 Brunswick Square London WC1N 1AX UK k.dziemidowicz@ucl.ac.uk g.williams@ucl.ac.uk.ORCID https://orcid.org/0000-0001-9586-6867
Delmiro Fernandez-ReyesDepartment of Computer Science, University College London 66-72 Gower Street London WC1E 6EA UK.ORCID https://orcid.org/0000-0001-5070-9198
Claire M SmithUCL Great Ormond Street Institute of Child Health, University College London 30 Guilford Street London WC1N 1EH UK.ORCID https://orcid.org/0000-0002-8913-0009
Karolina DziemidowiczUCL School of Pharmacy, University College London 29-39 Brunswick Square London WC1N 1AX UK k.dziemidowicz@ucl.ac.uk g.williams@ucl.ac.uk.
Gareth R WilliamsUCL School of Pharmacy, University College London 29-39 Brunswick Square London WC1N 1AX UK k.dziemidowicz@ucl.ac.uk g.williams@ucl.ac.uk.ORCID https://orcid.org/0000-0002-3066-2860

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory diseases, including influenza, infectious pneumonia, and severe acute respiratory syndrome (SARS), are a leading cause of morbidity and mortality worldwide. The recent COVID-19 pandemic claimed over 6.9 million lives globally. With the possibility of future pandemics, the creation of affordable antimicrobial meshes for protective gear, such as facemasks, is essential. Electrospinning has been a focus for much of this research, but most approaches are complex and expensive, often wasting raw materials by distributing antiviral agents throughout the mesh despite the fact they can only be active if at the fibre surface. Here, we report a low cost and efficient one-step method to produce nanofibre meshes with antimicrobial activity, including against SARS-CoV-2. Cetrimonium bromide (CTAB) was deposited directly onto the surface of polycaprolactone (PCL) fibres by coaxial electrospinning. The CTAB-coated samples have denser meshes with finer nanofibres than non-coated PCL fibres (mean diameter: ∼300 nm

Identifiers

PMID38957404
PMCPMC11216540

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.