Evidence map›Paper›PMID 38957335›Full record

ArticleEthiopian journal of health sciences2024

Malaria Diagnosis at the Pediatric Emergency Unit of a Teaching Hospital in Makurdi, North Central Nigeria.

A Michael, N B Samba, M G Adikwu, M O Ochoga, J U Akpan, E E Eseigbe

Abstract read
In one paragraph

Article in Ethiopian journal of health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

A MichaelDepartment of Pediatrics, Benue State University/ Benue State University Teaching Hospital, Makurdi.
N B SambaDepartment of Pediatrics, Benue State University Teaching Hospital, Makurdi.
M G AdikwuDepartment of Pediatrics, Benue State University Teaching Hospital, Makurdi.
M O OchogaDepartment of Pediatrics, Federal University of Health Sciences, Otukpo.
J U AkpanDepartment of Pediatrics, Federal Medical Center, Makurdi.
E E EseigbeDepartment of Pediatrics, Benue State University/ Benue State University Teaching Hospital, Makurdi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Globally, there were 241 million cases of malaria in 2020, with an estimated 627,000 deaths with Nigeria accounting for 27% of the global malaria cases. In sub-Saharan Africa, testing is low with only 28% of children with a fever receiving medical advice or a rapid diagnostic test in 2021. In Nigeria, there are documented reports of over-diagnosis and over-treatment of malaria in children. Therefore, this study examined the diagnosis of malaria at the Benue State University Teaching Hospital, Makurdi. Methods: A 5-year (2018-2022) retrospective study was carried out at the Emergency Pediatric Unit (EPU). Records of all children presenting to the EPU with an assessment of malaria were retrieved and reviewed. Data was analyzed using SPSS 23. Results: Out of 206 children reviewed, 128 (62.1%) were tested using either malaria RDT or microscopy while 78(37.9%) were not tested. Out of the number tested, 59(46.1%) were negative while 69(53.9%) tested positive, of which 14(20.3%) had uncomplicated malaria while 55(79.7%) had severe malaria. However, while 97.1% (n=67) of the positive cases were treated with IV artesunate, 69.5% (n=41) of those who tested negative and 88.5% (69) of those who were not tested also received IV artesunate. Moreover, while 85.5% (n=59) of those who tested positive received oral artemisinin-based combination therapy (ACT), 72.9% (n=43) of those who tested negative and 67.9% (53) of those who were not tested also received oral ACT. Conclusion: There was over-diagnosis of malaria, and subsequently, over-treatment. Hence continued emphasis on parasitological confirmation of malaria before treatment is recommended.

Indexed as

AntimalarialsEmergency Service, HospitalHospitals, TeachingMalariaAdolescentArtemisininsChildChild, PreschoolFemaleHumansInfantMaleNigeriaRetrospective StudiesAntimalarialsArtemisininsemergency unithospitalMalariaover-diagnosis

Identifiers

PMID38957335
PMCPMC11217796

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.