Evidence map›Paper›PMID 38956813›Full record

SynthesisBrain and behavior2024

Vision-related quality of life after unilateral occipital stroke.

Neil Dogra, Bryan V Redmond, Selena Lilley, Brent A Johnson, Byron L Lam, Madhura Tamhankar, Steven E Feldon, Berkeley Fahrenthold, Jingyi Yang, Krystel R Huxlin and 1 more

Erratum issuedAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Exogenous Spatial Attention Helps Overcome Spatial Specificity of Visual Learning in the Blind Field After V1 Damage.Journal of cognitive enhancement : towards the integration of theory and practice · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Neil DograDepartment of Ophthalmology, Flaum Eye Institute and Center for Visual Science, University of Rochester, Rochester, New York, USA.
Bryan V RedmondDepartment of Ophthalmology, Flaum Eye Institute and Center for Visual Science, University of Rochester, Rochester, New York, USA.ORCID 0000-0002-3716-3239
Selena LilleyDepartment of Ophthalmology, Flaum Eye Institute and Center for Visual Science, University of Rochester, Rochester, New York, USA.
Brent A JohnsonDepartment of Biostatistics and Computational Biology, University of Rochester, Rochester, New York, USA.
Byron L LamBascom Palmer Eye Institute, University of Miami, Miami, Florida, USA.
Madhura TamhankarScheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Steven E FeldonDepartment of Ophthalmology, Flaum Eye Institute and Center for Visual Science, University of Rochester, Rochester, New York, USA.
Berkeley FahrentholdDepartment of Ophthalmology, Flaum Eye Institute and Center for Visual Science, University of Rochester, Rochester, New York, USA.
Jingyi YangDepartment of Ophthalmology, Flaum Eye Institute and Center for Visual Science, University of Rochester, Rochester, New York, USA.
Krystel R HuxlinDepartment of Ophthalmology, Flaum Eye Institute and Center for Visual Science, University of Rochester, Rochester, New York, USA.
Matthew R CavanaughDepartment of Ophthalmology, Flaum Eye Institute and Center for Visual Science, University of Rochester, Rochester, New York, USA.ORCID 0000-0002-4277-5432

Funding

VISUAL SCIENCE RESEARCH CTR SUPPORTP30EY001319 · NEI · UNIVERSITY OF ROCHESTER · PI MICHELE RUCCI · 1985 to 2026
$17.5M
VISUAL SCIENCET32EY007125 · NEI · UNIVERSITY OF ROCHESTER · PI Krystel R Huxlin, Duje Tadin · 1990 to 2026
$7.1M
Vision recovery in cortical blindnessR01EY027314 · NEI · UNIVERSITY OF ROCHESTER · PI MARISA CARRASCO, Krystel R Huxlin · 2017 to 2026
$5.3M
Center of Emerging and Innovative Science for Empire State Development 1730C004Center of Excellence 1689bC2EnVision LLCNational Eye Institute and Office of Behavioral and Social Sciences Research R01 EY027314-05S1National Eye Institute and Office of Behavioral and Social Sciences Research R01 EY027314-05S2NEI NIH HHS P30 EY001319NEI NIH HHS R01 EY027314NEI NIH HHS T32 EY007125Research to Prevent Blindness
6 · The paper itself

Abstract

BACKGROUND/

objectivesStroke damage to the primary visual cortex induces large, homonymous visual field defects that impair daily living. Here, we asked if vision-related quality of life (VR-QoL) is impacted by time since stroke. SUBJECTS/

methodsWe conducted a retrospective meta-analysis of 95 occipital stroke patients (female/male = 26/69, 27-78 years old, 0.5-373.5 months poststroke) in whom VR-QoL was estimated using the National Eye Institute Visual Functioning Questionnaire (NEI-VFQ) and its 10-item neuro-ophthalmic supplement (Neuro10). Visual deficit severity was represented by the perimetric mean deviation (PMD) calculated from 24-2 Humphrey visual fields. Data were compared with published cohorts of visually intact controls. The relationship between VR-QoL and time poststroke was assessed across participants, adjusting for deficit severity and age with a multiple linear regression analysis.

resultsOccipital stroke patients had significantly lower NEI-VFQ and Neuro10 composite scores than controls. All subscale scores describing specific aspects of visual ability and functioning were impaired except for ocular pain and general health, which did not differ significantly from controls. Surprisingly, visual deficit severity was not correlated with either composite score, both of which increased with time poststroke, even when adjusting for PMD and age.

conclusionsVR-QoL appears to improve with time postoccipital stroke, irrespective of visual deficit size or patient age at insult. This may reflect the natural development of compensatory strategies and lifestyle adjustments. Thus, future studies examining the impact of rehabilitation on daily living in this patient population should consider the possibility that their VR-QoL may change gradually over time, even without therapeutic intervention.

Indexed as

Quality of LifeStrokeAdultAgedFemaleHumansMaleMiddle AgedOccipital LobeRetrospective StudiesVision DisordersVisual Fieldscortical blindnesshemianopiaquadrantanopiaquality of lifestroke

Identifiers

PMID38956813
PMCPMC11219293

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.