Evidence map›Paper›PMID 38956650›Full record

ArticleParasites & vectors2024

Is Culex modestus a New Usutu virus vector?

Alina Soto, Lotte Wauters, Leen Delang

Abstract read
In one paragraph

Article in Parasites & vectors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alina SotoDepartment of Microbiology, Immunology and Transplantation, Virus-Host Interactions & Therapeutic Approaches (VITA) Research Group, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Lotte WautersDepartment of Microbiology, Immunology and Transplantation, Virus-Host Interactions & Therapeutic Approaches (VITA) Research Group, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Leen DelangDepartment of Microbiology, Immunology and Transplantation, Virus-Host Interactions & Therapeutic Approaches (VITA) Research Group, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium. leen.delang@kuleuven.be.

Funding

KU Leuven C14/20/108
6 · The paper itself

Abstract

Usutu virus is an emerging pathogen transmitted by mosquitoes. Culex modestus mosquitoes are widespread in Europe, but their role in disease transmission is poorly understood. Recent data from a single infectious mosquito suggested that Culex modestus could be an unrecognized vector for Usutu virus. In this study, our aim was to corroborate this finding using a larger sample size. We collected immature Culex modestus from a reedbed pond in Flemish Brabant, Belgium, and reared them in the laboratory until the third generation. Adult females were then experimentally infected with Usutu virus in a blood meal and incubated at 25 °C for 14 days. The presence of Usutu virus in the saliva, head and body of each female was determined by plaque assay and quantitative real-time reverse-transcription polymerase chain reaction (qRT-PCR). The transmission efficiency was 54% (n = 15/28), confirming that Belgian Culex modestus can experimentally transmit Usutu virus.

Indexed as

CulexFlavivirusFlavivirus InfectionsMosquito VectorsAnimalsBelgiumFemaleSalivaArbovirusCulex modestusEmerging pathogenUsutu virusVector competence

Identifiers

PMID38956650
PMCPMC11218075

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.