ArticleBMC cancer2024
Patterns and trends in melanoma mortality in the United States, 1999-2020.
Article in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed.
- Geographic variation in the impact of novel melanoma therapies on mortality.Journal of the American Academy of Dermatology · 2026Article
- ChatGPT-Generated Advice on Sun Protection and Skin Cancer Prevention Compared to American Academy of Dermatology Guidelines: Cross-Sectional Content Analysis.JMIR dermatology · 2026Article
- Trends in Melanoma Prevalence and Risk Factors by Skin Reactions to Sun Exposure in the U.S. Population (1999-2018).Journal of racial and ethnic health disparities · 2026Article
- Article
- Predicting skin melanoma progression via LAG-3, TIGIT and HAVCR2.Functional & integrative genomics · 2026Article
- Risk Factors for Melanoma Survival: DGCR8 as a Predictive Factor for Mortality in Young Patients.Acta dermato-venereologica · 2026Article
- A tryptophan metabolism-related gene signature predicts prognosis and immune features in cutaneous melanoma.Frontiers in immunology · 2026Article
- MYC as a key target for melanoma therapy.Frontiers in cell and developmental biology · 2026Review
- A multiscale geospatial analysis integrating explainable machine learning to characterize spatial disparities in melanoma mortality associated with environmental justice and healthcare access in the contiguous United States.Frontiers in public health · 2026Article
- Melanoma Severity at Presentation and Prior Skin Cancer Screening: A Survey Study of Surgical Oncology Patients.Journal of skin cancer · 2026Article
- Evaluation of cytotoxic, anti-oxidant, and apoptotic effects ofIranian journal of basic medical sciences · 2026Article
- A combination of low TMB and PD-L1 expression predict poor progression-free survival of metastatic melanoma patients treated with first-line ipilimumab plus nivolumab.Frontiers in immunology · 2026Article
- U.S. Colorectal Cancer Mortality, 1999-2023: A 25-Year National Analysis of Trends and Disparities.Journal of gastrointestinal cancer · 2025Article
- Tattooing and risk of melanoma: a population-based case-control study in Utah.Journal of the National Cancer Institute · 2025Article
- Evaluating GPT-5 for Melanoma Detection Using Dermoscopic Images.Diagnostics (Basel, Switzerland) · 2025Article
- Harvesting Risk: An Ecologic Study of Agricultural Practices and Patterns and Melanoma Incidence in Pennsylvania.JCO clinical cancer informatics · 2025Article
- Phenotypic and Quantitative Characterization of Mast Cells in Cutaneous Melanoma: Correlation with Staging Metrics.Current issues in molecular biology · 2025Article
- Screening and novel diagnostic technologies for melanoma: an update.Melanoma management · 2025Review
- Alcohol Consumption and Melanoma in a Prospective United States Cohort Study: Results from the NIH-AARP Diet and Health Study.The Journal of nutrition · 2025Article
- Trends in Mesothelioma Mortality in the United States Between 1999 and 2020.JTO clinical and research reports · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMelanoma, a deadly form of skin cancer, has witnessed a notable increase in incidence over the past decades. Despite advancements in treatment, it remains a significant cause of cancer mortality. Understanding demographic trends and variations in melanoma mortality is crucial for addressing disparities and implementing effective interventions.
methodsUsing the Centers for Disease Control Wide Ranging Online Data for Epidemiologic Research (CDC WONDER) database, we analyzed melanoma mortality data in the United States from 1999 to 2020. Data were stratified by demographic and regional variables, and age-adjusted mortality rates were calculated. Descriptive analysis was performed and Joinpoint regression analysis was employed to identify temporal trends.
resultsBetween 1999 and 2020, there were 184,416 melanoma-related deaths in the United States Overall, the age-adjusted mortality rate declined from 2.7 to 2.0 per 100,000 people at a rate of -1.3% annually, with significant variations across demographic groups and regions. Men, non-Hispanic White individuals, and those aged > 65 experienced higher mortality rates. Non-Hispanic White individuals noted the steepest decrease in AAMR after 2013 at a rate of -6.1% annually. Disparities were seen by geographic density, with rural populations exhibiting higher mortality compared to their urban and suburban counterparts.
conclusionThe study highlights a significant reduction in melanoma mortality in the U.S. since 2013, potentially attributed to advancements in diagnostic techniques such as dermoscopy and the introduction of immune checkpoint inhibitors. Disparities persist, particularly among rural populations. Targeted interventions focusing on increased screening and education are warranted to further mitigate melanoma mortality and address demographic disparities.
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