Evidence map›Paper›PMID 38956534›Full record

ArticleBMC pediatrics2024

SARS-CoV-2 in Mozambican primary school-aged children at Maputo City and Province: a cross-sectional study from a low-income country.

Adilson Fernando Loforte Bauhofer, Édio Ussivane, Assucênio Chissaque, Fátima Iahaia, Ramígio Pololo, Fernanda Campos, Emerson Miranda, Luciana António, Plácida Maholela, Aline Gatambire and 5 more

Abstract read
In one paragraph

Article in BMC pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Adilson Fernando Loforte BauhoferInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique. adilsonbauhofer@gmail.com.
Édio UssivaneInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Assucênio ChissaqueInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Fátima IahaiaInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Ramígio PololoInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Fernanda CamposInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Emerson MirandaInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Luciana AntónioInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Plácida MaholelaInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Aline GatambireInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Marlene DjedjeInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Fátima RáiceInstituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Luzia GonçalvesInstituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, Lisboa, Portugal.
Nilsa de Deus *Instituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.
Osvaldo Inlamea *Instituto Nacional de Saúde (INS), EN1, Bairro da Vila-Parcela, Distrito de Marracuene, Província de Maputo, Mozambique.

Funding

Deutsche Forschungsgemeinschaft JO369/5-2Fundação para a Ciência e a Tecnologia UID/04413/2020"la Caixa" and the Calouste Gulbenkian foundations in the framework of the Support for Health Research Projects in PALOP Call for Proposals 260403
6 · The paper itself

Abstract

backgroundSeroprevalence studies provide information on the true extent of infection and capture demographic and geographic differences, indicating the level of immunity against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). We sought to provide local evidence of SARS-CoV-2 exposure in school-aged children during in-class teaching in Maputo City and Province, Mozambique.

methodsBetween August and November 2022, we performed a cross-sectional study in school-aged children in four schools in rural, peri-urban, and urban areas of Maputo City and Province. A point-of-care test was used to evaluate SARS-CoV-2 antigens and anti-SARS-CoV-2-specific immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies. Descriptive statistics were used to estimate the prevalence of the antigens and antibodies. Multiple logistic regression models were used to estimate the adjusted odds ratio (AOR) for the factors associated with anti-SARS-CoV-2 antibodies.

resultsA total of 736 school-aged children were analyzed. The prevalence of the SARS-CoV-2 antigen was 0.5% (4/736). The prevalence of SARS-CoV-2 antigens was 0.0% (0/245), 0.8% (2/240) and 0.8% (2/251), in the rural, peri-urban and urban areas respectively. The overall seroprevalence of the anti-SARS-CoV-2 antibodies (IgG or IgM) was 80.7% (594/736). In rural area anti-SARS-CoV-2 IgG or IgM antibodies were detected in 76.7% (188/245), while in peri-urban area they were detected in 80.0% (192/240) and in urban area they were detected in 85.3% (214/251). In the adjusted logistic regression model, school-aged children from the urban area were more likely to have anti-SARS-CoV-2 IgG or IgM antibodies than were school-aged children from the rural area (adjusted odds ratio: 1.679; 95% CI: 1.060-2.684; p-value = 0.028).

conclusionsDuring the in-class teaching period, active SARS-CoV-2 cases in school-aged children were observed. More than half of the school-aged children were exposed to SARS-CoV-2, and SARS-CoV-2 was significantly more common in the schools at the urban area than in the school in the rural area at Maputo City and Province.

Indexed as

Antibodies, ViralCOVID-19SARS-CoV-2ChildCross-Sectional StudiesFemaleHumansImmunoglobulin GImmunoglobulin MMaleMozambiquePrevalenceSchoolsSeroepidemiologic StudiesAntibodies, ViralImmunoglobulin GImmunoglobulin MMaputo-MozambiquePrevalenceSARS-CoV-2School-aged children

Identifiers

PMID38956534
PMCPMC11221092

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.