Evidence map›Paper›PMID 38956496›Full record

ArticleBMC cancer2024

SerpinB2 deficiency is associated with delayed mammary tumor development and decreased pro-tumorigenic macrophage polarization.

Yin Ji Piao, Hoe Suk Kim, Hyelim Kim, Jun Shen, Woo Kyung Moon

Abstract read
In one paragraph

Article in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. PIEZO2 in tumors: from mechanobiological switches to activity-targeted therapies.Journal of experimental & clinical cancer research : CR · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yin Ji Piao *Department of Radiology, Sun Yat-Sen Memorial Hospital and Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou, 510120, China.
Hoe Suk Kim *Department of Biomedical Sciences, Seoul National University College of Medicine, 103 Daehak-Ro, Jongno-Gu, Seoul, 03080, Korea.
Hyelim KimDepartment of Biomedical Sciences, Seoul National University College of Medicine, 103 Daehak-Ro, Jongno-Gu, Seoul, 03080, Korea.
Jun ShenDepartment of Radiology, Sun Yat-Sen Memorial Hospital and Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou, 510120, China. shenjun@mail.sysu.edu.cn.
Woo Kyung MoonDepartment of Biomedical Sciences, Seoul National University College of Medicine, 103 Daehak-Ro, Jongno-Gu, Seoul, 03080, Korea. moonwk@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The in vivo functions of SerpinB2 in tumor cells and tumor-associated macrophages (TAMs) during breast cancer development and metastasis remain elusive. SerpinB2-deficient MMTV-PyMT mice (PyMT

Indexed as

Breast NeoplasmsPlasminogen Activator Inhibitor 2AnimalsCell Line, TumorCell MovementFemaleHumansIntracellular Signaling Peptides and ProteinsMacrophagesMammary Neoplasms, ExperimentalMiceMice, KnockoutNitric Oxide Synthase Type IIRAW 264.7 CellsTumor-Associated MacrophagesIntracellular Signaling Peptides and ProteinsNitric Oxide Synthase Type IIPlasminogen Activator Inhibitor 2Breast cancerMMTV-PyMT transgenic mouseSerpinB2Tumor-associated macrophage

Identifiers

PMID38956496
PMCPMC11221169

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.