ArticleBMC psychiatry2024
Interaction effects between sleep-related disorders and depression on hypertension among adults: a cross-sectional study.
Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Between Depression and Risk of Hypertension: A Systematic Review and Meta-Analysis.Brain and behavior · 2025Pooled it
- Depressive Symptom Trajectories and Incident Pain: The Role of Nocturnal Sleep Duration in Two Prospective Cohort Studies.Journal of prevention (2022) · 2026Article
- Sleep disorders among elderly hypertensive patients: associated factors and implications for management.Frontiers in cardiovascular medicine · 2026Article
- Association Between Sleep Quality and Cognitive Function in Patients with Hypertension in Rural Areas of Shanxi Province, China: The Chain Mediating Role of Anxiety and Depression.Psychology research and behavior management · 2026Article
- Falls, Sleep Disorders and Cognitive Frailty in Hospitalized Older Adults with Hypertension:A Cross-Sectional Study.Clinical interventions in aging · 2025Article
- Prevalence of sleep disturbance and associated factors among nurses in Chinese tertiary public hospitals: a national cross-sectional study.Frontiers in public health · 2025Article
- Article
- Construction of an index system of core competence assessment for sleep medicine nurse specialists in China: a Delphi study.BMC nursing · 2024Article
- Prevalence and Risk by Age and Sex of Sleep Dysregulation and Depressive Episodes in Bipolar and Depressive Disorders in a Community Survey in Sardinia, Italy.Journal of clinical medicine · 2024Article
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Authors and funding
9 authors.
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Abstract
backgroundHypertension, sleep disorders, and depression represent notable public health issues, and their interconnected nature has long been acknowledged. The objective of this study is to explore the interplay between sleep disorders and depression in the context of hypertension.
methodsThis cross-sectional study involved 42,143 participants aged 18 and above from the NHANES database across seven survey cycles between 2005 and 2018. After excluding those with missing data on depression, sleep disorders, and hypertension, as well as incomplete main variables, 33,383 participants remained. We used weighted logistic regression to examine the relationship between sleep disorders, depression, and hypertension. Additionally, we assessed the interaction between sleep disorders and depression on hypertension using both multiplicative and additive approaches to quantify their combined effect.
resultsCompared to individuals without sleep disorders, those with sleep disorders have an increased risk of hypertension (OR = 1.51, 95% CI: 1.37-1.67). Furthermore, individuals with depression experience a significantly higher risk of hypertension compared to those with sleep disorders alone (OR = 2.34, 95% CI: 1.95-2.80). Our study reveals a positive interaction between sleep disorders and depression in relation to hypertension risk (OR = 1.07, 95% CI: 1.02-1.13). In addition, we observed the quantitative additive interaction indicators (RERI = 0.73, 95% CI: 0.56 ~ 0.92; API = 0.31, 95% CI: 0.11 ~ 0.46; SI = 2.19, 95% CI: 1.08-3.46) influencing hypertension risk. Furthermore, our research also identified that individuals with less than 7 h of sleep, a sleep latency period between 5 and 30 min, or a latency period exceeding 30 min experience a significantly increased risk of hypertension.
conclusionsOur research uncovered separate links between sleep disorders, depression, and hypertension prevalence. Moreover, we identified an interaction between depression and sleep disorders in hypertension prevalence. Enhancing mental well-being and tackling sleep disorders could help prevent and manage hypertension. Yet, more investigation is required to establish causation and clarify mechanisms.
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