Evidence map›Paper›PMID 38956480›Full record

SynthesisBMC public health2024

Mapping global prevalence of menopausal symptoms among middle-aged women: a systematic review and meta-analysis.

Yiqiao Fang, Fen Liu, Xinyue Zhang, Lei Chen, Yang Liu, Lin Yang, Xiaofeng Zheng, Jiaye Liu, Kewei Li, Zhihui Li

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. FIGO best practice recommendations for the mental health of women at menopausal age.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Guideline
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Trends in Government-Subsidised Menopausal Hormone Therapy Dispensing in Australia Between 2014 and 2023.The Australian & New Zealand journal of obstetrics & gynaecology · 2026
    Article
  19. Observational
  20. Neurologic Complications of Pregnancy and Menopause.Continuum (Minneapolis, Minn.) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yiqiao Fang *Division of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, No.37 Guoxue Road, Chengdu, Sichuan, 610041, China.
Fen Liu *Department of Operating Room, West China School of Nursing, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Xinyue ZhangDepartment of Respiratory and Critical Care Medicine, Frontiers Science Center for Disease-related Molecular Network, Center of Precision Medicine, Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Lei ChenDivision of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, No.37 Guoxue Road, Chengdu, Sichuan, 610041, China.
Yang LiuDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, 400010, China.
Lin YangDepartment of Gynecology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, 400010, China.
Xiaofeng ZhengDepartment of Endocrinology and Metabolism, Center for Diabetes and Metabolism Research, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Jiaye LiuDivision of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, No.37 Guoxue Road, Chengdu, Sichuan, 610041, China.
Kewei LiDepartment of Pediatric Department, West China Hospital, Sichuan University, No.37 Guoxue Road, Chengdu, Sichuan, 610041, China. vivian5225133@outlook.com.
Zhihui LiDivision of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, No.37 Guoxue Road, Chengdu, Sichuan, 610041, China. rockoliver@vip.sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWomen at middle age are puzzled by a series of menopausal disturbances, can be distressing and considerably affect the personal, social and work lives. We aim to estimate the global prevalence of nineteen menopausal symptoms among middle-aged women by performing a systematic review and meta-analysis.

methodsComprehensive search was performed in multiple databases from January, 2000 to March, 2023 for relevant studies. Random-effect model with double-arcsine transformation was used for data analysis.

resultsA total of 321 studies comprised of 482,067 middle-aged women were included for further analysis. We found varied prevalence of menopausal symptoms, with the highest prevalence of joint and muscular discomfort (65.43%, 95% CI 62.51-68.29) and lowest of formication (20.5%, 95% CI 13.44-28.60). Notably, South America shared dramatically high prevalence in a sort of menopausal symptoms including depression and urogenital symptoms. Besides, countries with high incomes (49.72%) had a significantly lower prevalence of hot flashes than those with low (65.93%), lower-middle (54.17%), and upper-middle (54.72%, p < 0.01), while personal factors, such as menopausal stage, had an influence on most menopausal symptoms, particularly in vaginal dryness. Prevalence of vagina dryness in postmenopausal women (44.81%) was 2-fold higher than in premenopausal women (21.16%, p < 0.01). Furthermore, a remarkable distinction was observed between body mass index (BMI) and prevalence of sleep problems, depression, anxiety and urinary problems.

conclusionThe prevalence of menopausal symptoms affected by both social and personal factors which calls for attention from general public.

Indexed as

Hot FlashesMenopauseFemaleGlobal HealthHumansMiddle AgedPrevalenceMenopauseMiddle-aged womenPrevalencePsychologicalSomaticUrogenital

Identifiers

PMID38956480
PMCPMC11220992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.