Evidence map›Paper›PMID 38956472›Full record

Trial reportBMC anesthesiology2024

Effect of cuff inflation with lidocaine, saline, and air on tracheal tube cuff pressure during laparoscopic resection of colorectal neoplasms: a randomized clinical trial.

Xuan Wang, Jie Zhang, Guangli Zhu, Shenquan Cai, Qingtong Zhang, Manlin Duan, Shanwu Feng

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuan WangDepartment of Anesthesiology, Women's Hospital of Nanjing Medical University, Nanjing Women and Children's HealthCare Hospital, No.123 Tianfei Lane, Mochou Road, Nanjing, 210011, Jiangsu Province, P.R. China.
Jie ZhangDepartment of Anesthesiology, Affiliated Jinling Hospital, Medical School, Nanjing University, Nanjing, Jiangsu Province, P.R. China.
Guangli ZhuDepartment of Anesthesiology, Li Huili Hospital Affiliated to Ningbo University, Ningbo, Zhejiang Province, P.R. China.
Shenquan CaiDepartment of Anesthesiology, Affiliated Jinling Hospital, Medical School, Nanjing University, Nanjing, Jiangsu Province, P.R. China.
Qingtong ZhangDepartment of Anesthesiology, Affiliated Jinling Hospital, Medical School, Nanjing University, Nanjing, Jiangsu Province, P.R. China.
Manlin Duan *Department of Anesthesiology, Nanjing BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, No. 71 Hexi Avenue, Jianye District, Nanjing, Jiangsu Province, 210019, P.R. China. dml1200@126.com.
Shanwu Feng *Department of Anesthesiology, Women's Hospital of Nanjing Medical University, Nanjing Women and Children's HealthCare Hospital, No.123 Tianfei Lane, Mochou Road, Nanjing, 210011, Jiangsu Province, P.R. China. shanwufeng@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTracheal tube cuff pressure will increase after pneumoperitoneum when the cuff is inflated with air, high pressure can cause tracheal mucosal damage. This prospective trial aimed to assess if inflating with normal saline or lidocaine can prevent increase of tracheal tube cuff pressure and tracheal mucosal damage in laparoscopic surgeries with general anesthesia. Whether changes of tracheal tube cuff transverse diameter (CD) can predict changes of tracheal tube cuff pressure.

methodsNinety patients scheduled for laparoscopic resection of colorectal neoplasms under general anesthesia were randomly assigned to groups air (A), saline (S) or lidocaine (L). Endotracheal tube cuff was inflated with room-temperature air in group A (n = 30), normal saline in group S (n = 30), 2% lidocaine hydrochloride injection in group L (n = 30). After intubation, tracheal tube cuff pressure was monitored by a calibrated pressure transducers, cuff pressure was adjusted to 25 cmH

resultsTracheal tube cuff pressure had no significant difference among the three groups at T

conclusionsCompared to inflation with air, normal saline and 2% lidocaine cannot ameliorate the increase of tracheal tube cuff pressure during the pneumoperitoneum period under general anesthesia, but lidocaine can decrease postoperative tracheal mucosa injury. ΔCD measured by ultrasound is a predictor for changes of tracheal tube cuff pressure.

trial registrationChinese Clinical Trial Registry, identifier: ChiCTR2100054089, Date: 08/12/2021.

Indexed as

Colorectal NeoplasmsIntubation, IntratrachealLaparoscopyLidocainePressureSaline SolutionAdultAgedAirAnesthesia, GeneralAnesthetics, LocalFemaleHumansMaleMiddle AgedPneumoperitoneum, ArtificialAnesthetics, LocalLidocaineSaline SolutionEndotracheal tube cuff pressureLaparoscopic surgeryLidocaineNormal salineTracheal mucosa injury

Identifiers

PMID38956472
PMCPMC11218051

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.