Evidence map›Paper›PMID 38956469›Full record

Trial reportBMC anesthesiology2024

Effect of pericapsular nerve group block and suprainguinal fascia iliaca block on postoperative analgesia and stress response in elderly patients undergoing hip arthroplasty: a prospective randomized controlled double-blind trial.

Xiaozhen Cui, Zhi Cheng, Tianyu Zhang, Hai Xu, Hengfei Luan, Jiying Feng, Xiaobao Zhang, Pin Zhu

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06534697 (Analgesic Efficacy of Fascia Iliaca Block for Postoperative Pain Control After Elective Hip Arthroplasty), which is not on this map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06534697 nanot yet recruitingnot on this map

Analgesic Efficacy of Fascia Iliaca Block for Postoperative Pain Control After Elective Hip Arthroplasty: a Randomised Controlled Study

TypeinterventionalSponsorFoisor Orthopedics Clinical HospitalRan2024 to 2025Enrolled210ConditionsHip OsteoarthritisArmsNaropin, 0.2% Injectable Solution in Sodium chloride, Naropin, 0.2% Injectable Solution in dextrose 5%, Dextrose 10 % in Water
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pericapsular nerve group block for total hip arthroplasty: A systematic review.The Journal of international medical research · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Pericapsular nerve group block reduces fentanyl use in transcatheter aortic valve implantation: a randomized prospective study.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaozhen CuiDepartment of Anesthesiology, Graduate Training Base of Lianyungang First People's Hospital of Jinzhou Medical University, Lianyungang, Jiangsu, People's Republic of China.
Zhi ChengDepartment of Anesthesiology, The First People's Hospital of Lianyungang, No. 6 East Zhenhua Road, Lianyungang, Jiangsu, People's Republic of China.
Tianyu ZhangDepartment of Anesthesiology, Graduate Training Base of Lianyungang First People's Hospital of Jinzhou Medical University, Lianyungang, Jiangsu, People's Republic of China.
Hai XuDepartment of Anesthesiology, Graduate Training Base of Lianyungang First People's Hospital of Jinzhou Medical University, Lianyungang, Jiangsu, People's Republic of China.
Hengfei LuanDepartment of Anesthesiology, The First People's Hospital of Lianyungang, No. 6 East Zhenhua Road, Lianyungang, Jiangsu, People's Republic of China.
Jiying FengDepartment of Anesthesiology, The First People's Hospital of Lianyungang, No. 6 East Zhenhua Road, Lianyungang, Jiangsu, People's Republic of China.
Xiaobao ZhangDepartment of Anesthesiology, The First People's Hospital of Lianyungang, No. 6 East Zhenhua Road, Lianyungang, Jiangsu, People's Republic of China.
Pin ZhuDepartment of Anesthesiology, The First People's Hospital of Lianyungang, No. 6 East Zhenhua Road, Lianyungang, Jiangsu, People's Republic of China. zhupin198348@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs a novel regional analgesic technique, ultrasound-guided pericapsular nerve group (PENG) block has some potential advantages, and we designed a randomized clinical trial (RCT) to investigate whether the ultrasound-guided PENG block combined with general anesthesia can better reduce stress response, maintain intraoperative hemodynamic stability, and reduce postoperative analgesia in elderly hip arthroplasty compared with ultrasound-guided suprainguinal fascia iliaca block (SIFIB) combined with general anesthesia.

methodsSeventy-four subjects were enrolled over an 8-month period (20 April 2023 to 31 December 2023). All patients were divided into the test group (group P) and the control group (group S) using the envelope as the randomization method. The test group was treated with preoperative ultrasound-guided PENG block analgesia combined with general anesthesia and the control group was treated with preoperative ultrasound-guided SIFIB analgesia combined with general anesthesia. The primary outcome selected was the patient Visual Analogue Scale (VAS) score at 12 h postoperatively.

resultsAfter generalized estimating equations (GEE) analysis, there was a statistically significant difference in the main effect of postoperative VAS score in group P compared with group S (P = 0.009), the time effect of VAS score in each group was significantly different (P < 0.001), and there was no statistically significant difference in the group-time interaction effect (P = 0.069). There was no statistically significant difference in the main effect of intraoperative mean arterial pressure (MAP) change (P = 0.911), there were statistically significant differences in the time effect of MAP in each group (P < 0.001), and there were statistically significant differences in the interaction effect (P < 0.001).

conclusionsIn summary, we can conclude that in elderly patients undergoing hip fracture surgery, postoperative analgesia is more pronounced, intraoperative hemodynamic parameters are more stable, and intraoperative stress is less induced in patients receiving SIFIB than in patients receiving PENG block.

Indexed as

Arthroplasty, Replacement, HipNerve BlockPostoperative PainUltrasonography, InterventionalAgedAged, 80 and overAnesthesia, GeneralDouble-Blind MethodFasciaFemaleHumansMaleProspective StudiesStress, PhysiologicalElderly patientsHemodynamicsNerve blockPostoperative analgesiaStress response

Identifiers

PMID38956469
PMCPMC11218169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.