Evidence map›Paper›PMID 38956322›Full record

ReviewNature metabolism2024

Towards nutrition with precision: unlocking biomarkers as dietary assessment tools.

Cătălina Cuparencu, Tuğçe Bulmuş-Tüccar, Jan Stanstrup, Giorgia La Barbera, Henrik M Roager, Lars O Dragsted

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
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  6. Trial
  7. Review
  8. Article
  9. Human-Centered Innovation: Precision Nutrition and the Future of Food.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Advancing Precision Nutrition Through Multimodal Data and Artificial Intelligence.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  15. Article
  16. Review
  17. Review
  18. Advancing personalised and precision nutrition.Journal of nutritional science · 2026
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cătălina CuparencuDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Frederiksberg, Denmark. cup@nexs.ku.dk.ORCID http://orcid.org/0000-0003-3889-5498
Tuğçe Bulmuş-TüccarDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Frederiksberg, Denmark.
Jan StanstrupDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Frederiksberg, Denmark.
Giorgia La BarberaDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Frederiksberg, Denmark.ORCID http://orcid.org/0000-0003-0583-906X
Henrik M RoagerDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Frederiksberg, Denmark.ORCID http://orcid.org/0000-0002-2504-8313
Lars O DragstedDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Frederiksberg, Denmark.ORCID http://orcid.org/0000-0003-0609-6317

Funding

Carlsbergfondet (Carlsberg Foundation) CF15-0574Novo Nordisk Fonden (Novo Nordisk Foundation) NNF19OC0056246
6 · The paper itself

Abstract

Precision nutrition requires precise tools to monitor dietary habits. Yet current dietary assessment instruments are subjective, limiting our understanding of the causal relationships between diet and health. Biomarkers of food intake (BFIs) hold promise to increase the objectivity and accuracy of dietary assessment, enabling adjustment for compliance and misreporting. Here, we update current concepts and provide a comprehensive overview of BFIs measured in urine and blood. We rank BFIs based on a four-level utility scale to guide selection and identify combinations of BFIs that specifically reflect complex food intakes, making them applicable as dietary instruments. We discuss the main challenges in biomarker development and illustrate key solutions for the application of BFIs in human studies, highlighting different strategies for selecting and combining BFIs to support specific study designs. Finally, we present a roadmap for BFI development and implementation to leverage current knowledge and enable precision in nutrition research.

Indexed as

BiomarkersNutrition AssessmentDietEatingFeeding BehaviorHumansNutritional StatusPrecision MedicineBiomarkers

Identifiers

PMID38956322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.