ArticleScientific reports2024
Association between admission pan-immune-inflammation value and short-term mortality in septic patients: a retrospective cohort study.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Association of the pan-immune-inflammation value with 60-day in-hospital mortality in critically ill patients with acute myocardial infarction: evidence from the MIMIC-IV database.BMC cardiovascular disorders · 2026Article
- Comparative Prognostic Performance of HALP, PIV, and Naples Prognostic Score in Critically Ill Patients with Sepsis: A Retrospective Multicentre Cohort Study.Journal of clinical medicine · 2026Article
- Diagnostic value of the pan-immune inflammation value in methanol-induced optic neuropathy.Irish journal of medical science · 2026Article
- The Relationship Between the Pan-Immune-Inflammation Value (PIV) and Mortality in Elderly Critically Ill Patients with Sepsis: A Single-Centre Retrospective Study.Journal of clinical medicine · 2026Article
- Pan-Immune-Inflammation Value for Mortality Risk Stratification in Critically Ill Patients With Acute Ischemic Stroke: A Cohort Study Based on the MIMIC-IV Database.CNS neuroscience & therapeutics · 2026Article
- The clinical values of laboratory inflammatory and composite indices in predicting rapidly progressive interstitial lung disease and prognosis in anti-MDA5 dermatomyositis patients.Clinical rheumatology · 2026Article
- Association between pan-immune-inflammation and in-hospital mortality in critically ill patients with acute pancreatitis: a cohort study from the MIMIC-IV database.BMC gastroenterology · 2026Article
- Observational
- Pan-immune-inflammation value predicts 2-year recurrence after chemoradiotherapy in nasopharyngeal carcinoma.Frontiers in medicine · 2026Article
- Multicenter cohort study reveals: composite inflammatory indexs are associated with increased risk of diabetes in patients with hypertension.Frontiers in endocrinology · 2026Article
- Pan immune inflammation value improves MELD 3.0 for mortality prediction in critically ill cirrhotic patients.Scientific reports · 2025Article
- Prediction model for postoperative acute kidney injury in non-cardiac surgical patients: a retrospective cohort study.BMC nephrology · 2025Article
- Prognostic value of the pan-immune-inflammation value for mortality in sepsis-induced coagulopathy: a Medical Information Mart for Intensive Care study.Research and practice in thrombosis and haemostasis · 2025Article
- Pan-Immune Inflammation Value as a Novel Comprehensive Predictor of In-Hospital Mortality in Patients with Severe Burns: A Single-Center Retrospective Analysis.Medicina (Kaunas, Lithuania) · 2025Article
- Pan-immune-inflammation value and mortality in the US adult MASLD: a nonlinear NHANES analysis.BMC gastroenterology · 2025Article
- New Systemic Inflammatory Indices as Predictors of Fulminant Myocarditis in Children.Diagnostics (Basel, Switzerland) · 2025Article
- The association between pan-immune-inflammation value with mortality in critically ill patients with sepsis-associated acute kidney injury.BMC infectious diseases · 2025Article
- Association of PIV value with early mortality in ICU patients with sepsis-associated acute kidney injury from the MIMIC IV database.Scientific reports · 2025Article
- Association of Inflammatory and Metabolic Markers with Mortality in Patients with Postoperative Femur Fractures in the Intensive Care Unit.Medicina (Kaunas, Lithuania) · 2025Article
- Prognostic role of the systemic immune-inflammation index and pan-immune-inflammation value in acute methanol poisoning.Turkish journal of medical sciences · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pan-Immune-Inflammation Value (PIV) has recently received more attention as a novel indicator of inflammation. We aimed to evaluate the association between PIV and prognosis in septic patients. Data were extracted from the Medical Information Mart for Intensive Care IV database. The primary and secondary outcomes were 28-day and 90-day mortality. The association between PIV and outcomes was assessed by Kaplan-Meier curves, Cox regression analysis, restricted cubic spline curves and subgroup analysis. A total of 11,331 septic patients were included. Kaplan-Meier curves showed that septic patients with higher PIV had lower 28-day survival rate. In multivariable Cox regression analysis, log2-PIV was positively associated with the risk of 28-day mortality [HR (95% CI) 1.06 (1.03, 1.09), P < 0.001]. The relationship between log2-PIV and 28-day mortality was non-linear with a predicted inflection point at 8. To the right of the inflection point, high log2-PIV was associated with an increased 28-day mortality risk [HR (95% CI) 1.13 (1.09, 1.18), P < 0.001]. However, to the left of this point, this association was non-significant [HR (95% CI) 1.01 (0.94, 1.08), P = 0.791]. Similar results were found for 90-day mortality. Our study showed a non-linear relationship between PIV and 28-day and 90-day mortality risk in septic patients.
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