Evidence map›Paper›PMID 38956291›Full record

ArticleScientific reports2024

Association between parental decisions regarding abortion and severity of fetal heart disease.

Masahiro Nakao, Masanari Kuwabara, Mika Saito, Chinami Horiuchi, Hiroko Morisaki, Kanako Kishiki, Yuji Hamamichi, Izumi Orui, Ryoko Ono, Ryo Suzuki and 14 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Masahiro NakaoDepartment of Obstetrics and Gynecology, Sakakibara Heart Institute, Tokyo, Japan. hiro.nakao1987@gmail.com.
Masanari KuwabaraDivision of Public Healh, Center for Community Medicine, and Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Mika SaitoDepartment of Pediatric Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Chinami HoriuchiDepartment of Obstetrics and Gynecology, Sakakibara Heart Institute, Tokyo, Japan.
Hiroko MorisakiDepartment of Medical Genetics, Sakakibara Heart Institute, Tokyo, Japan.
Kanako KishikiDepartment of Pediatric Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Yuji HamamichiDepartment of Pediatric Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Izumi OruiDepartment of Medical Genetics, Sakakibara Heart Institute, Tokyo, Japan.
Ryoko OnoDepartment of Obstetrics and Gynecology, Sakakibara Heart Institute, Tokyo, Japan.
Ryo SuzukiDepartment of Obstetrics and Gynecology, Sakakibara Heart Institute, Tokyo, Japan.
Miho IzawaDepartment of Obstetrics and Gynecology, Sakakibara Heart Institute, Tokyo, Japan.
Yoshiki MaedaDepartment of Obstetrics and Gynecology, Sakakibara Heart Institute, Tokyo, Japan.
Azumi OhmoriDepartment of Obstetrics and Gynecology, Sakakibara Heart Institute, Tokyo, Japan.
Tomomi UyedaDepartment of Pediatric Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Satoshi YazakiDepartment of Pediatric Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Tadahiro YoshikawaDepartment of Pediatric Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Naoki WadaDepartment of Pediatric Cardiac Surgery, Sakakibara Heart Institute, Tokyo, Japan.
Toru HosodaDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Masafumi NiiDepartment of Obstetrics and Gynecology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-0001, Japan.
Kayo TanakaDepartment of Obstetrics and Gynecology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-0001, Japan.
Hiroaki TanakaDepartment of Obstetrics and Gynecology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-0001, Japan.
Eiji KondoDepartment of Obstetrics and Gynecology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-0001, Japan.
Yukihiro TakahashiDepartment of Pediatric Cardiac Surgery, Sakakibara Heart Institute, Tokyo, Japan.
Tomoaki IkedaDepartment of Obstetrics and Gynecology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-0001, Japan.

Funding

Sakakibara Internal Research Grant for Promotion of Sciences, 2022 H-36-2022
6 · The paper itself

Abstract

The prenatal diagnosis of fetal heart disease potentially influences parental decision-making regarding pregnancy termination. Existing literature indicates that the severity, whether in complexity or lethality, significantly influences parental decisions concerning abortion. However, questions remain as to how fetal heart disease severity impacts parental decisions, given recent advancements in postsurgical outcomes. Therefore, we investigated risk factors associated with parents' decision-making regarding abortion following a prenatal diagnosis of fetal heart disease. Our analysis included 73 (terminated: n = 37; continued: n = 36) pregnancies with a fetal heart disease diagnosed before 22 weeks of gestation. Increased gestational age at diagnosis reduced the likelihood of parents' decision on termination (Model 1: adjusted odds ratio, 0.94; 95% confidence interval 0.89-0.99; Model 2: 0.95 0.90-0.997). Critical disease (5.25; 1.09-25.19) and concurrent extracardiac or genetic abnormalities (Model 1: 4.19, 1.21-14.53; Model 2: 5.47, 1.50-19.96) increased the likelihood of choosing abortion. Notably, complex disease did not significantly influence parental decisions (0.56; 0.14-2.20). These results suggest that parental decision-making regarding abortion may be influenced by earlier gestational age at diagnosis, the lethality of heart disease, and extracardiac or genetic abnormalities, but not its complexity if prenatal diagnosis and parental counseling are provided at a cardiovascular-specialized facility.

Indexed as

Abortion, InducedDecision MakingParentsPrenatal DiagnosisAdultFemaleFetal DiseasesGestational AgeHeart Defects, CongenitalHeart DiseasesHumansMalePregnancyRisk FactorsSeverity of Illness Index

Identifiers

PMID38956291
PMCPMC11220094

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.