ArticleTranslational psychiatry2024
The impact of REM sleep loss on human brain connectivity.
Article in Translational psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- REM sleep reduction leads to fear overgeneralization via negatively modulating prefrontal theta oscillations.BMC medicine · 2025Trial
- Default mode network and visual network responsiveness to transcutaneous auricular vagus nerve stimulation predict its variable efficacy in primary insomnia disorder.Frontiers in neurology · 2025Trial
- Sleep and Drug Use: Neuroimaging Evidence for a Multidimensional Brain Framework.Biological psychiatry · 2026Review
- Prevalence and clinical implications of Rapid eye movement sleep behavior disorder in Alzheimer's disease and Lewy body dementia.GeroScience · 2026Observational
- Neuroimaging subtypes of adolescent sleep insufficiency stratify natural short sleepers from comorbidity or environment driven insufficiency.Nature communications · 2026Article
- Effect of Ang II Receptor Inhibition on GSK-3β/CREB/BDNF Signalling in REM Sleep Deprivation-Induced Memory Impairment.Neurochemical research · 2026Article
- From Brain Networks to Sleep Perception: EEG-Derived Global Efficiency is Associated with Subjective Sleep Quality in University Students.Nature and science of sleep · 2026Article
- Differential Resting-State Brain Activity Following Early- and Late-Night Sleep Loss.Neuroscience bulletin · 2025Article
- Chronotype as a potential risk factor for cognitive decline: The mediating role of sleep quality and health behaviours in a 10-year follow-up study.The journal of prevention of Alzheimer's disease · 2025Article
- The Specificity of Metacognition Questionnaire-30 Subdimensions: Findings From Connectome-Based Predictive Modeling.Depression and anxiety · 2025Article
- Altered functional network topology and connectivity in female nurses with shift work sleep disorder.Frontiers in systems neuroscience · 2025Article
- Increased Steps in Japanese Older Adults Associated with Improved Winter Sleep Quality.Gerontology & geriatric medicineArticle
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain function is vulnerable to the consequences of inadequate sleep, an adverse trend that is increasingly prevalent. The REM sleep phase has been implicated in coordinating various brain structures and is hypothesized to have potential links to brain variability. However, traditional imaging research have encountered challenges in attributing specific brain region activity to REM sleep, remained understudied at the whole-brain connectivity level. Through the spilt-night paradigm, distinct patterns of REM sleep phases were observed among the full-night sleep group (n = 36), the early-night deprivation group (n = 41), and the late-night deprivation group (n = 36). We employed connectome-based predictive modeling (CPM) to delineate the effects of REM sleep deprivation on the functional connectivity of the brain (REM connectome) during its resting state. The REM sleep-brain connectome was characterized by stronger connectivity within the default mode network (DMN) and between the DMN and visual networks, while fewer predictive edges were observed. Notably, connections such as those between the cingulo-opercular network (CON) and the auditory network, as well as between the subcortex and visual networks, also made significant contributions. These findings elucidate the neural signatures of REM sleep loss and reveal common connectivity patterns across individuals, validated at the group level.
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