Evidence map›Paper›PMID 38955904›Full record

ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2025

Candida albicans in the oral cavities of pets: biofilm formation, putative virulence, antifungal resistance profiles and classification of the isolates.

Harun Hizlisoy, Adalet Dishan, Ilknur Karaca Bekdik, Mukaddes Barel, Kursat Koskeroglu, Yasin Ozkaya, Oznur Aslan, Omer Tolga Yilmaz

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Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Harun HizlisoyFaculty of Veterinary Medicine, Department of Veterinary Public Health, Erciye University, Kayseri, Türkiye. hizlisoy@erciyes.edu.tr.
Adalet DishanFaculty of Veterinary Medicine, Department of Food Hygiene and Technology, Bozok University, Yozgat, Türkiye.
Ilknur Karaca BekdikFaculty of Veterinary Medicine, Department of Internal Medicine, Erciyes University, Kayseri, Türkiye.
Mukaddes BarelFaculty of Veterinary Medicine, Department of Veterinary Public Health, Erciye University, Kayseri, Türkiye.
Kursat KoskerogluHealth Sciences Institute, Erciyes University, Kayseri, Türkiye.
Yasin OzkayaHealth Sciences Institute, Erciyes University, Kayseri, Türkiye.
Oznur AslanFaculty of Veterinary Medicine, Department of Internal Medicine, Erciyes University, Kayseri, Türkiye.
Omer Tolga YilmazHealth Sciences Institute, Erciyes University, Kayseri, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aimed to investigate Candida albicans presence, antifungal resistance, biofilm formation, putative virulence genes, and molecular characterization in oral samples of dogs and cats. A total of 239 oral samples were collected from cats and dogs of various breeds and ages at Erciyes University, Faculty of Veterinary Medicine Clinics, between May 2017 and April 2018. Among 216 isolates obtained, 15 (6.95%) were identified as C. albicans, while 8 (3.7%) were non-albicans Candida species. Antifungal susceptibility testing revealed sensitivities to caspofungin, fluconazole, and flucytosine in varying proportions. Molecular analysis indicated the presence of fluconazole and caspofungin resistance genes in all C. albicans isolates. Additionally, virulence genes ALS1, HWP1, and HSP90 showed variable presence. Biofilm formation varied among isolates, with 46.7% strong, 33.3% moderate, and 20% weak producers. PCA analysis categorized isolates into two main clusters, with some dog isolates grouped separately. The findings underscore the significance of oral care and protective measures in pets due to C. albicans prevalence, biofilm formation, virulence factors, and antifungal resistance in their oral cavity, thereby aiding clinical diagnosis and treatment in veterinary medicine.

Indexed as

Antifungal AgentsBiofilmsCandida albicansCandidiasis, OralDrug Resistance, FungalMouthPetsAnimalsCat DiseasesCatsDog DiseasesDogsFungal ProteinsMicrobial Sensitivity TestsVirulenceVirulence FactorsAntifungal AgentsFungal ProteinsVirulence FactorsAntifungal susceptibilityBiofilmCandida albicansCats and dogsMALDI-TOF MS

Identifiers

PMID38955904

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.