ArticleAnnals of biomedical engineering2026
Probabilistic Finite Element Analysis of Human Rib Biomechanics: A Framework for Improved Generalizability.
Article in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Advances in Musculoskeletal Modeling of the Thoraco-Lumbar Spine: A Comprehensive Systematic Review.Annals of biomedical engineering · 2025Pooled it
- Modeling Fatigue and Damage Development in the Annulus Fibrosus Using a Reactive Viscoelastic Framework.Annals of biomedical engineering · 2026Article
- Investigating the Impact of Blunt Force Trauma: A Probabilistic Study of Behind Armor Blunt Trauma Risk.Annals of biomedical engineering · 2026Article
- The I-PREDICT 50th Percentile Male Finite Element Model: Development and Validation of the Torso.Annals of biomedical engineering · 2026Article
- The I-PREDICT 50th Percentile Male Finite Element Model: Development and Validation of the Torso.Annals of biomedical engineering · 2026Article
- The I-PREDICT 50th Percentile Male Warfighter Finite Element Model: Development and Validation of the Head and Neck.Annals of biomedical engineering · 2026Article
- Large Language Models in Injury Prediction Tools: Simplifying User Interactions and Improving Risk Interpretation.Annals of biomedical engineering · 2026Article
- Lateral Cortical Fixation as the Optimal Strategy for Achieving Stability in Rib Fractures: A Patient-Specific Finite Element Analysis.Bioengineering (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
In dynamic impact events, thoracic injuries often involve rib fractures, which are closely related to injury severity. Previous studies have investigated the behavior of isolated ribs under impact loading conditions, but often neglected the variability in anatomical shape and tissue material properties. In this study, we used probabilistic finite element analysis and statistical shape modeling to investigate the effect of population-wide variability in rib cortical bone tissue mechanical properties and rib shape on the biomechanical response of the rib to impact loading. Using the probabilistic finite element analysis results, a response surface model was generated to rapidly investigate the biomechanical response of an isolated rib under dynamic anterior-posterior load given the variability in rib morphometry and tissue material properties. The response surface was used to generate pre-fracture force-displacement computational corridors for the overall population and a population sub-group of older mid-sized males. When compared to the experimental data, the computational mean response had a RMSE of 4.28N (peak force 94N) and 6.11N (peak force 116N) for the overall population and sub-group respectively, whereas the normalized area metric when comparing the experimental and computational corridors ranged from 3.32% to 22.65% for the population and 10.90% to 32.81% for the sub-group. Furthermore, probabilistic sensitivities were computed in which the contribution of uncertainty and variability of the parameters of interest was quantified. The study found that rib cortical bone elastic modulus, rib morphometry and cortical thickness are the random variables that produce the largest variability in the predicted force-displacement response. The proposed framework offers a novel approach for accounting biological variability in a representative population and has the potential to improve the generalizability of findings in biomechanical studies.
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Registered trials
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