ArticleOpen biology2024
Distinct molecular profile of the chick organizer as a stem zone during axial elongation.
Article in Open biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Cell biology of the chick organizer: Origins, composition, population dynamics and fate.Cells & development · 2025Review
- The organizer as a cooperative of signaling cells for neural induction.bioRxiv : the preprint server for biology · 2025Article
- Distinct molecular profile of the chick organizer as a stem zone during axial elongation.Open biology · 2024Article
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Authors and funding
3 authors.
Funding
Abstract
The vertebrate organizer plays a crucial role in building the main (antero-posterior) axis of the embryo: it neuralizes the surrounding ectoderm, and is the site of emigration for cells making axial and paraxial mesendoderm during elongation. The chick organizer becomes a stem zone at the onset of elongation; it stops recruiting cells from the neighbouring ectoderm and generates all its derivatives from the small number of resident cells it contains at the end of gastrulation stages. Nothing is known about the molecular identity of this stem zone. Here, we specifically labelled long-term resident cells of the organizer and compared their RNA-seq profile to that of the neighbouring cell populations. Screening by reverse transcription-polymerase chain reaction and
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