Evidence map›Paper›PMID 38954989›Full record

Trial reportGynecologic oncology2024

Improving the palliative-procedure decision-making process for patients with peritoneal carcinomatosis: A secondary analysis.

Jaclyn A Wall, Rachel A Pozzar, Andrea C Enzinger, Anna Tavormina, Catherine Howard, Ursula A Matulonis, Joyce F Liu, Neil Horowitz, Larissa A Meyer, Alexi A Wright

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Gynecologic oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jaclyn A WallUniversity of Alabama at Birmingham, Birmingham, AL, United States. Electronic address: jarquiette@uabmc.edu.
Rachel A PozzarDana-Farber Cancer Institute, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.
Andrea C EnzingerDana-Farber Cancer Institute, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.
Anna TavorminaDana-Farber Cancer Institute, Boston, MA, United States.
Catherine HowardDana-Farber Cancer Institute, Boston, MA, United States.
Ursula A MatulonisDana-Farber Cancer Institute, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.
Joyce F LiuDana-Farber Cancer Institute, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.
Neil HorowitzDana-Farber Cancer Institute, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.
Larissa A MeyerThe University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Alexi A WrightDana-Farber Cancer Institute, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.

Funding

BOLSTER: Strengthening Patient and Caregiver Supports in Advanced Gynecologic and Gastrointestinal Cancers - a Multi-Site Randomized Controlled TrialR01CA270040 · NCI · DANA-FARBER CANCER INST · PI Alexi A Wright · 2023 to 2026
$2.8M
Strengthening Patient and Caregiver Supports in Ovarian Cancer with Palliative Care: Pilot RCT of BOLSTERR21CA223684 · NCI · DANA-FARBER CANCER INST · PI WRIGHT, ALEXI A · 2019 to 2020
$419k
Development and Pilot Testing of a Collaborative Agenda-Setting Intervention to Promote Patient-Centered Communication in Ovarian Cancer CareK23NR020219 · NINR · DANA-FARBER CANCER INST · PI POZZAR, RACHEL · 2023 to 2025
$401k
AHRQ HHS T32 HS013852NCI NIH HHS R01 CA270040NCI NIH HHS R21 CA223684NINR NIH HHS K23 NR020219
6 · The paper itself

Abstract

backgroundPeritoneal carcinomatosis (PC) is common in patients with advanced gynecologic and gastrointestinal cancers. Frequently, patients with PC undergo palliative surgery or procedures to manage disease-related complications and side effects. However, there are limited data regarding patients' and family caregivers' decision-making processes about these procedures. Thus, we sought to describe the decision-making experiences of patients with PC who elect to pursue palliative surgical procedures and their family caregivers.

methodsWe conducted a secondary analysis of qualitative data collected during a pilot randomized controlled trial of BOLSTER, a nurse-led telehealth intervention for patients with PC and their caregivers after an acute hospitalization and palliative procedure. Participants in both study arms described their experiences in semi-structured interviews. We re-analyzed coded qualitative data with a focus on understanding decision-making experiences surrounding palliative surgery and procedures using conventional content analysis.

resultsInterviews from 32 participants, 23 patients and 9 caregivers, were analyzed. Participants reported their decision-making was complicated by illness uncertainty and a desire for clear, effective communication with surgical and medical oncology teams. Participants requested more information about the impact of palliative procedures on their daily life. Several also noted that, without improved understanding, a misalignment between patient and family caregiver goals and palliative procedures may inadvertently increase suffering.

conclusionDiscussions related to patients' goals and preferences can improve the quality of treatment decision-making in patients with PC and their caregivers. Future research should test interventions to improve advanced cancer patients' illness understanding and decision-making surrounding palliative surgery and procedures.

Indexed as

Decision MakingPalliative CarePeritoneal NeoplasmsAdultAgedCaregiversFemaleGenital Neoplasms, FemaleHumansMiddle AgedPilot ProjectsQualitative ResearchTelemedicineDecision-makingPalliative proceduresPeritoneal carcinomatosis

Identifiers

PMID38954989
PMCPMC11740732

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.