Evidence map›Paper›PMID 38954547›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Nanoparticle-assisted tubulin assembly is environment dependent.

Mahima Unnikrishnan, Yuhan Wang, Martin Gruebele, Catherine J Murphy

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mahima UnnikrishnanDepartment of Chemistry, University of Illinois Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0003-2530-7036
Yuhan WangCenter for Biophysics and Quantitative Biology, University of Illinois Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0001-6807-3968
Martin GruebeleDepartment of Chemistry, University of Illinois Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0001-9291-8123
Catherine J MurphyDepartment of Chemistry, University of Illinois Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0001-7066-5575

Funding

National Science Foundation (NSF) CHE-2001611National Science Foundation (NSF) MCB 2205665
6 · The paper itself

Abstract

Nanomaterials acquire a biomolecular corona upon introduction to biological media, leading to biological transformations such as changes in protein function, unmasking of epitopes, and protein fibrilization. Ex vivo studies to investigate the effect of nanoparticles on protein-protein interactions are typically performed in buffer and are rarely measured quantitatively in live cells. Here, we measure the differential effect of silica nanoparticles on protein association in vitro vs. in mammalian cells. BtubA and BtubB are a pair of bacterial tubulin proteins identified in

Indexed as

Bacterial ProteinsNanoparticlesSilicon DioxideTubulinFluorescence Resonance Energy TransferHumansMicrotubulesProtein BindingProtein MultimerizationBacterial ProteinsSilicon DioxideTubulinbacterial tubulinFRETnanoparticle–protein coronaprotein assembly

Identifiers

PMID38954547
PMCPMC11252952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.