ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2024
Procedural and Intermediate-term Results of the Electroanatomical-guided Cardioneuroablation for the Treatment of Supra-Hisian Second- or Advanced-degree Atrioventricular Block: the PIRECNA multicentre registry.
Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Cardioneuroablation for Reflex Syncope and Functional Bradyarrhythmias: A State-of-the-Art Review.Journal of clinical medicine · 2026Review
- Convolutional neural network for real‑time localization of ganglionated plexi from bipolar intracardiac electrograms.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Cardioneuroablation: A Comprehensive Review.Reviews in cardiovascular medicine · 2026Review
- Empirical Anatomical Versus HAFE-Guided Cardioneuroablation for Vasovagal Syncope: Long-Term Efficacy and Safety Outcomes.Clinical cardiology · 2026Article
- Efficacy and safety of cardioneuroablation as a treatment for patients with functional bradyarrhythmia: a systematic review and meta-analysis.International journal of cardiology. Heart & vasculature · 2026Review
- Article
- A tailored approach to cardioneuroablation for reflex syncope and functional bradycardia: results from the ELEGANCE multicentre study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Older age is not an independent predictor of syncope recurrence following cardioneuroablation for reflex syncope.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Observational
- Intracardiac echocardiography guided anatomical approach to cardioneuroablation: feasibility and outcomes.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- Intracardiac echocardiography and electroanatomical mapping: do we still need fluoroscopy for cardioneuroablation procedures?Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Article
- Cardioneuroablation for Asystolic Reflex Syncope: How to Identify the Best Candidate and How to Predict Success.Arrhythmia & electrophysiology review · 2025Review
- Cardioneuroablation for treatment of atrioventricular block: to cure the patient or the electrocardiogram?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Article
- TELE-SPACER - a randomized clinical trial protocol: Cardioneuroablation versus pacemaker implantation in the treatment of vagally-mediated atrio-ventricular block.Cardiology journal · 2024Article
- Cardioneuroablation: the known and the unknown.Frontiers in cardiovascular medicine · 2024Review
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30 authors.
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No grant is acknowledged in the PubMed record.
Abstract
aimsPrior case series showed promising results for cardioneuroablation in patients with vagally induced atrioventricular blocks (VAVBs). We aimed to examine the acute procedural characteristics and intermediate-term outcomes of electroanatomical-guided cardioneuroablation (EACNA) in patients with VAVB. METHODS AND
resultsThis international multicentre retrospective registry included data collected from 20 centres. Patients presenting with symptomatic paroxysmal or persistent VAVB were included in the study. All patients underwent EACNA. Procedural success was defined by the acute reversal of atrioventricular blocks (AVBs) and complete abolition of atropine response. The primary outcome was occurrence of syncope and daytime second- or advanced-degree AVB on serial prolonged electrocardiogram monitoring during follow-up. A total of 130 patients underwent EACNA. Acute procedural success was achieved in 96.2% of the cases. During a median follow-up of 300 days (150, 496), the primary outcome occurred in 17/125 (14%) cases with acute procedural success (recurrence of AVB in 9 and new syncope in 8 cases). Operator experience and use of extracardiac vagal stimulation were similar for patients with and without primary outcomes. A history of atrial fibrillation, hypertension, and coronary artery disease was associated with a higher primary outcome occurrence. Only four patients with primary outcome required pacemaker placement during follow-up.
conclusionThis is the largest multicentre study demonstrating the feasibility of EACNA with encouraging intermediate-term outcomes in selected patients with VAVB. Studies investigating the effect on burden of daytime symptoms caused by the AVB are required to confirm these findings.
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