ArticleJapanese journal of radiology2024
Characterization of accurate 3D collimator-detector response function for single- and multi-lofthole collimated SPECT cameras.
Article in Japanese journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- Generative AI and large language models in nuclear medicine: current status and future prospects.Annals of nuclear medicine · 2024Review
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Abstract
purposeCollimator-detector response function (CDRF) of a SPECT scanner refers to the image generated from a point source of activity. This research aims to characterize the CDRF of a breast-dedicated SPECT imager equipped with a lofthole collimator using GATE Monte Carlo simulation. MATERIALS AND
methodsTo do so, a cylindrical multi-lofthole collimation system with lofthole apertures dedicated to breast imaging was modeled using the GATE Monte Carlo simulator. The dependency of the CDRF on the source-to-collimator distance of a single-lofthole as well as 8-lofthole collimations was assessed and then compared. In addition, the 3D-sensitivity map of the 8-lofthole collimation was derived. Finally, fair comparisons were conducted between the response of the 8-lofthole collimator and that of an 8-pinhole and also existing analytical derivations. In all cases, a data acquisition period of 5.0 min with an in-air
resultsFor the single-lofthole collimator, 4.5 times increasing the magnification factor leads to a 16- and twofold improvement in the sensitivity and spatial resolution, respectively. In the single-lofthole collimator, the resolution and sensitivity are degraded as the source-to-aperture distance increases. For the cylindrical 8-lofthole collimator, the findings confirm that CDRF strongly depends on source-to-aperture distance and angle of photon incidence. For a 30 mm in-plane offset point, a 25% increase in sensitivity is observed compared to that of the center of the FOV. Increasing the angle from 0
conclusionIn conclusion, both spatial resolution and sensitivity of the lofthole collimation are considerably angle- and offset-dependent within the FOV of single- and multi-lofthole collimated SPECT imagers.
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