Evidence map›Paper›PMID 38953970›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2024

Exploring the link between metformin use and adhesive capsulitis of the shoulder: a retrospective cohort study in Taiwan.

Bing-Sian Lin, Wu-Chien Chien, Chieh-Hua Lu, Chi-Hsiang Chung, Chang-Huei Tsao, Tzu-Hsuan Weng, Ching-Yueh Lin

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bing-Sian LinDepartment of Dermatology, Tri-Service General Hospital, Taipei City, Taiwan.
Wu-Chien ChienDepartment of Medical Research, Tri-Service General Hospital, Taipei City, Taiwan. chienwu@mail.ndmctsgh.edu.tw.
Chieh-Hua LuSchool of Medicine, National Defense Medical Center, Taipei City, Taiwan. ndeca2001@gmail.com.
Chi-Hsiang ChungDepartment of Medical Research, Tri-Service General Hospital, Taipei City, Taiwan.
Chang-Huei TsaoDepartment of Medical Research, Tri-Service General Hospital, Taipei City, Taiwan.
Tzu-Hsuan WengDepartment of Medical Research, Tri-Service General Hospital, Taipei City, Taiwan.
Ching-Yueh LinSchool of Medicine, National Defense Medical Center, Taipei City, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The risk of adhesive capsulitis of shoulder in diabetic patients taking metformin has not been evaluated. We aimed for evaluating the relative risk of adhesive capsulitis of shoulder in diabetic patients taking metformin at the level of the whole country population. We conducted a retrospective cohort study using a national health insurance database in Taiwan from 2000 to2015. We used International Classification of Diseases, Ninth Revision, to categorise the medical condition for study group and comparison group. We used Cox proportional hazard regression analyses to determined adjusted hazard ratios (aHRs) of adhesive capsulitis of shoulder between study and comparison group after adjusting for sex, age, and comorbidities.Among 30,412 diabetic patients using metformin, 3020 patients were diagnosis with adhesive capsulitis of shoulder during follow up. Of the 121,648 patients without the use of metformin, 11,375 patients developed adhesive capsulitis of shoulder. Adhesive capsulitis of shoulder risk was elevated in patients taking metformin than in non-metformin group (adjusted hazard ratio [HR] 1.179, 95% confidence interval [95% CI] 1.022 to 1.268; p = 0.039). Risk of adhesive capsulitis of shoulder among the diabetic patients taking metformin was higher than those did not taking metformin.

Indexed as

BursitisHypoglycemic AgentsMetforminAdultAgedCohort StudiesDatabases, FactualDiabetes MellitusFemaleHumansMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesRisk FactorsShoulder JointHypoglycemic AgentsMetforminAdhesive capsulitis of shoulderCohort studyDiabetes mellitusFrozen shoulderMetformin

Identifiers

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.