Evidence map›Paper›PMID 38953698›Full record

ArticleAutism research : official journal of the International Society for Autism Research2024

Examining the association between prenatal cannabis exposure and child autism traits: A multi-cohort investigation in the environmental influences on child health outcome program.

Chaela Nutor, Aisha S Dickerson, Tingju Hsu, Aseel Al-Jadiri, Carlos A Camargo, Julie B Schweitzer, Coral L Shuster, Margaret R Karagas, Juliette C Madan, Bibiana Restrepo and 7 more

Abstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Chaela NutorDepartment of Psychology, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-5469-2802
Aisha S DickersonDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0003-3929-9540
Tingju HsuDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Aseel Al-JadiriInstitute for Child Development, Hackensack University Medical Center, Hackensack, New Jersey, USA.
Carlos A CamargoMassachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Julie B SchweitzerSchool of Medicine, University of California, Sacramento, California, USA.
Coral L ShusterWomen and Infants Hospital of Rhode Island, Providence, Rhode Island, USA.
Margaret R KaragasGeisel School of Medicine, Hanover, New Hampshire, USA.
Juliette C MadanDepartment of Pediatrics, Psychiatry & Epidemiology, Children's Hospital at Dartmouth, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Bibiana RestrepoDepartment of Pediatrics, University of California Davis School of Medicine, MIND Institute, Sacramento, California, USA.ORCID 0000-0002-2341-7357
Rebecca J SchmidtDepartment of Public Health Sciences and the MIND Institute, University of California Davis School of Medicine, Davis, California, USA.ORCID 0000-0003-1582-2747
Claudia Lugo-CandelasIrving Medical Center, Columbia University, New York, New York, USA.
Jenae NeiderhiserDepartment of Psychology, Pennsylvania State University, University Park, Pennsylvania, USA.
Sheela SathyanarayanaDepartment of Pediatrics, University of Washington, Seattle, Washington, USA.
Anne L DunlopDepartment of Gynecology and Obstetrics, Emory University, Atlanta, Georgia, USA.
Patricia A BrennanDepartment of Psychology, Emory University, Atlanta, Georgia, USA.
program collaborators for Environmental influences on Child Health Outcomes

Funding

Project-005U2COD023375 · OD · DUKE UNIVERSITY · PI Linda S Adair, Phillip Brian Smith · 2016 to 2026
$215.9M
ECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4M
Wisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUH3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern · 2018 to 2026
$64.8M
The NYU Children’s Health & Environment Study: an ECHO CohortUH3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Akhgar Ghassabian, Leonardo Trasande · 2018 to 2026
$59.5M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyUH3OD023275 · OD · DARTMOUTH COLLEGE · PI MARGARET Rita KARAGAS, Juliette Madan · 2018 to 2026
$44.3M
The ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
Environmental Influences on Childhood Outcomes in the Northern Plains Safe Passage Study CohortsUH3OD023279 · OD · AVERA MCKENNAN · PI Amy J Elliott, Christine W Hockett · 2018 to 2026
$31.7M
Early Life Exposure to Endocrine Disrupting Chemicals and Child Growth, Adiposity, and NeurodevelopmentUH3OD023289 · OD · KAISER FOUNDATION RESEARCH INSTITUTE · PI ASSIAMIRA FERRARA, Monique Marie Hedderson · 2018 to 2026
$25.1M
Understanding Breastfeeding Practices Among ECHO Cohort Participants Before and During/After the COVID-19 PandemicUH3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI Charles James Barone, MICHAEL R. ELLIOTT · 2018 to 2026
$24.5M
Environmental influences on Child Health Outcomes (ECHO) program U24OD023319Environmental influences on Child Health Outcomes (ECHO) program U24OD023382Environmental influences on Child Health Outcomes (ECHO) program U2COD023375Environmental influences on Child Health Outcomes (ECHO) program UH3OD023244Environmental influences on Child Health Outcomes (ECHO) program UH3OD023249Environmental influences on Child Health Outcomes (ECHO) program UH3OD023251Environmental influences on Child Health Outcomes (ECHO) program UH3OD023253Environmental influences on Child Health Outcomes (ECHO) program UH3OD023271Environmental influences on Child Health Outcomes (ECHO) program UH3OD023272Environmental influences on Child Health Outcomes (ECHO) program UH3OD023275Environmental influences on Child Health Outcomes (ECHO) program UH3OD023279Environmental influences on Child Health Outcomes (ECHO) program UH3OD023282Environmental influences on Child Health Outcomes (ECHO) program UH3OD023285Environmental influences on Child Health Outcomes (ECHO) program UH3OD023286Environmental influences on Child Health Outcomes (ECHO) program UH3OD023289Environmental influences on Child Health Outcomes (ECHO) program UH3OD023290Environmental influences on Child Health Outcomes (ECHO) program UH3OD023305Environmental influences on Child Health Outcomes (ECHO) program UH3OD023313Environmental influences on Child Health Outcomes (ECHO) program UH3OD023318Environmental influences on Child Health Outcomes (ECHO) program UH3OD023320Environmental influences on Child Health Outcomes (ECHO) program UH3OD023328Environmental influences on Child Health Outcomes (ECHO) program UH3OD023337Environmental influences on Child Health Outcomes (ECHO) program UH3OD023342Environmental influences on Child Health Outcomes (ECHO) program UH3OD023347Environmental influences on Child Health Outcomes (ECHO) program UH3OD023349Environmental influences on Child Health Outcomes (ECHO) program UH3OD023365Environmental influences on Child Health Outcomes (ECHO) program UH3OD023389National Institute of Environmental Health Science K01ES032046NCATS NIH HHS UL1 TR004419NHLBI NIH HHS R01 HL159701NIEHS NIH HHS K01 ES032046NIEHS NIH HHS P30 ES036084NIH HHS U24 OD023319NIH HHS U24 OD023382NIH HHS U2C OD023375NIH HHS UG3 OD023282NIH HHS UH3 OD023244NIH HHS UH3 OD023249NIH HHS UH3 OD023251NIH HHS UH3 OD023253NIH HHS UH3 OD023271NIH HHS UH3 OD023272NIH HHS UH3 OD023275NIH HHS UH3 OD023279NIH HHS UH3 OD023282NIH HHS UH3 OD023285NIH HHS UH3 OD023286NIH HHS UH3 OD023289NIH HHS UH3 OD023290NIH HHS UH3 OD023305NIH HHS UH3 OD023313NIH HHS UH3 OD023318NIH HHS UH3 OD023320NIH HHS UH3 OD023328NIH HHS UH3 OD023337NIH HHS UH3 OD023342NIH HHS UH3 OD023347NIH HHS UH3 OD023349NIH HHS UH3 OD023365NIH HHS UH3 OD023389
6 · The paper itself

Abstract

This study examined the association between prenatal cannabis exposure and autism spectrum disorder (ASD) diagnoses and traits. A total sample of 11,570 children (ages 1-18; 53% male; 25% Hispanic; 60% White) from 34 cohorts of the National Institutes of Health-funded environmental influences on child health outcomes consortium were included in analyses. Results from generalized linear mixed models replicated previous studies showing that associations between prenatal cannabis exposure and ASD traits in children are not significant when controlling for relevant covariates, particularly tobacco exposure. Child biological sex did not moderate the association between prenatal cannabis exposure and ASD. In a large sample and measuring ASD traits continuously, there was no evidence that prenatal cannabis exposure increases the risk for ASD. This work helps to clarify previous mixed findings by addressing concerns about statistical power and ASD measurement.

Indexed as

Autism Spectrum DisorderCannabisPrenatal Exposure Delayed EffectsAdolescentChildChild HealthChild, PreschoolCohort StudiesFemaleHumansInfantMalePregnancyUnited Statesautism spectrum disorderbiological sexgestational agemulti‐cohort studyneurodevelopmentprenatal cannabis exposureprenatal risk factors

Identifiers

PMID38953698
PMCPMC11341247

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.