Evidence map›Paper›PMID 38953528›Full record

ArticleAnnals of surgery2025

Full Robotic Whole Graft Liver Transplantation: A Step Into The Future.

Hugo Pinto-Marques, Mafalda Sobral, Paolo Magistri, Sílvia Gomes da Silva, Gian Piero Guerrini, Raquel Mega, Cristiano Guidetti, João Santos Coelho, Stefano Di Sandro, Fabrizio Di Benedetto

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Article in Annals of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Advanced robotic liver surgery.Surgical endoscopy · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Achievements, Challenges and Promises of Minimally Invasive Liver Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Review
  9. Article
  10. [Advances in minimally invasive surgical techniques for liver transplant recipients].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Review
  11. Article
  12. A Foreword.Updates in surgery · 2025
    Article
  13. Article
  14. Full Robotic Whole Graft Liver Transplantation: A Novel Approach.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Minimally Invasive Liver Transplantation: The Recipient Operation.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Hugo Pinto-MarquesHepato-Biliary-Pancreatic and Transplantation Centre, Curry Cabral Hospital/Local Health Unit of São José, and NOVA Medical School, Lisbon, Portugal.
Mafalda SobralHepato-Biliary-Pancreatic and Transplantation Centre, Curry Cabral Hospital/Local Health Unit of São José, and NOVA Medical School, Lisbon, Portugal.
Paolo MagistriHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University Hospital of Modena "Policlinico", University of Modena and Reggio Emilia, Modena, Italy.
Sílvia Gomes da SilvaHepato-Biliary-Pancreatic and Transplantation Centre, Curry Cabral Hospital/Local Health Unit of São José, and NOVA Medical School, Lisbon, Portugal.
Gian Piero GuerriniHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University Hospital of Modena "Policlinico", University of Modena and Reggio Emilia, Modena, Italy.
Raquel MegaHepato-Biliary-Pancreatic and Transplantation Centre, Curry Cabral Hospital/Local Health Unit of São José, and NOVA Medical School, Lisbon, Portugal.
Cristiano GuidettiHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University Hospital of Modena "Policlinico", University of Modena and Reggio Emilia, Modena, Italy.
João Santos CoelhoHepato-Biliary-Pancreatic and Transplantation Centre, Curry Cabral Hospital/Local Health Unit of São José, and NOVA Medical School, Lisbon, Portugal.
Stefano Di SandroHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University Hospital of Modena "Policlinico", University of Modena and Reggio Emilia, Modena, Italy.
Fabrizio Di BenedettoHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University Hospital of Modena "Policlinico", University of Modena and Reggio Emilia, Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report the first European series of full robotic whole liver transplantation (RLT) with technical details and future perspectives.

backgroundFew cases of liver transplantation with a minimally invasive approach using partial grafts have been reported so far, and no cases of robotic whole liver transplantation have been reported in the scientific literature.

methodsThe adopted technique was full robotic liver hepatectomy, followed by robotic implantation after graft introduction through a small midline incision. Patients presenting with hepatocellular carcinoma in liver cirrhosis with a small caudate lobe, low degree of portal hypertension, no porto-mesenteric thrombosis, as well as low Model for End-Stage Liver Disease patients have been considered ideal candidates.

resultsSix patients underwent RLT between February and March 2024 at Lisbon and Modena University Liver Transplant Centers. Warm ischemia time during RLT ranged between 55 and 90 minutes, with a total surgery duration between 440 and 710 minutes. The median total operative time was 595 (±111.3) minutes. Only 1 recipient had prolonged hyperbilirubinemia, which was safely treated. The median in-hospital stay was 7.5 days (±4.8 d).

conclusionsRLT is a promising technique to further reduce the impact of liver transplantation thanks to smaller incision, gentle tissue manipulation, high magnification and precision for vascular and biliary anastomosis, and reduced postoperative pain. This is the first step toward the demonstration of the feasibility of minimally invasive surgery in liver transplantation, although further selection and technical refinements are needed to improve reproducibility.

Indexed as

HepatectomyLiver TransplantationRobotic Surgical ProceduresAdultAgedCarcinoma, HepatocellularFemaleHumansLiver NeoplasmsMaleMiddle AgedOperative Time

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.