Evidence map›Paper›PMID 38953461›Full record

ArticleFuture medicinal chemistry2024

Thiourea-functionalized aminoglutethimide derivatives as anti-leishmanial agents.

Muhammad Sajid, Hina Siddiqui, Humaira Zafar, Sammer Yousuf, Michael D Threadgill, Muhammad Iqbal Choudhary

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muhammad SajidH.E.J. Research Institute of Chemistry, International Center for Chemical & Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.ORCID 0009-0005-3104-0878
Hina SiddiquiH.E.J. Research Institute of Chemistry, International Center for Chemical & Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.ORCID 0000-0003-0432-2237
Humaira ZafarDr. Panjwani Center for Molecular Medicine & Drug Research, International Center for Chemical & Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.ORCID 0000-0003-2104-3862
Sammer YousufH.E.J. Research Institute of Chemistry, International Center for Chemical & Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.ORCID 0000-0002-8870-3581
Michael D ThreadgillDepartment of Life Sciences, University of Bath, Bath, BA2 7AY, UK.ORCID 0009-0003-9541-5451
Muhammad Iqbal ChoudharyH.E.J. Research Institute of Chemistry, International Center for Chemical & Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.ORCID 0000-0001-5356-3585

Funding

UK Research and Innovation's Global Challenges Research Fund, under the project agreement 'A Global Network for Neglected Tropical Diseases' MR/P027989/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antiprotozoal AgentsLeishmania majorLeishmania tropicaThioureaAnimalsHumansMolecular Docking SimulationMolecular StructureParasitic Sensitivity TestsStructure-Activity RelationshipAntiprotozoal AgentsThiourea(±)-Aminoglutethimidecutaneous leishmaniasiscytotoxicitythiourea

Identifiers

PMID38953461
PMCPMC11370960

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.