Evidence map›Paper›PMID 38953370›Full record

ArticleApplied and environmental microbiology2024

Expansion of Auxiliary Activity Family 5 sequence space via biochemical characterization of six new copper radical oxidases.

Jessica K Fong, Yann Mathieu, Minh Tri Vo, Annie Bellemare, Adrian Tsang, Harry Brumer

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Copper Radical Oxidases Contribute to Virulence inPathogens (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jessica K FongMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0009-0006-6194-2933
Yann MathieuMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
Minh Tri VoCentre for Structural and Functional Genomics, Concordia University, Montreal, Quebec, Canada.
Annie BellemareCentre for Structural and Functional Genomics, Concordia University, Montreal, Quebec, Canada.
Adrian TsangCentre for Structural and Functional Genomics, Concordia University, Montreal, Quebec, Canada.
Harry BrumerMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-0101-862X

Funding

Canadian Government | Natural Sciences and Engineering Research Council of Canada (NSERC) CREATE 509257-18Canadian Government | Natural Sciences and Engineering Research Council of Canada (NSERC) RGPIN-2018-03892Canadian Government | Natural Sciences and Engineering Research Council of Canada (NSERC) STPGP 493781-16Genome British Columbia (Genome BC) LSARP 10405Genome Canada (GC) LSARP 10405Genome Quebec LSARP 10405
6 · The paper itself

Abstract

Bacterial and fungal copper radical oxidases (CROs) from Auxiliary Activity Family 5 (AA5) are implicated in morphogenesis and pathogenesis. The unique catalytic properties of CROs also make these enzymes attractive biocatalysts for the transformation of small molecules and biopolymers. Despite a recent increase in the number of characterized AA5 members, especially from subfamily 2 (AA5_2), the catalytic diversity of the family as a whole remains underexplored. In the present study, phylogenetic analysis guided the selection of six AA5_2 members from diverse fungi for recombinant expression in

Indexed as

CopperOxidoreductasesPhylogenyAlcohol OxidoreductasesAmino Acid SequenceCatalytic DomainFungal ProteinsGalactose OxidaseRecombinant ProteinsSaccharomycetalesSequence AlignmentSubstrate SpecificityAlcohol Oxidoreductasesaryl-alcohol oxidaseCoppercopper oxidaseFungal ProteinsGalactose OxidaseOxidoreductasesRecombinant Proteinsalcohol oxidaseAuxiliary Activity Family 5carbohydrate-active enzymecopper radical oxidasegalactose oxidaseHMF oxidase

Identifiers

PMID38953370
PMCPMC11267884

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.