Evidence map›Paper›PMID 38953100›Full record

ReviewEpilepsy & behavior reports2024

Functional neurological disorder, physical activity and exercise: What we know and what we can learn from comorbid disorders.

Kelly A Boylan, Barbara A Dworetzky, Gaston Baslet, Ginger Polich, M Angela O'Neal, Claus Reinsberger

Abstract readReview
In one paragraph

Review in Epilepsy & behavior reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelly A BoylanDivision of Epilepsy and Neurology, Brigham and Women's Hospital, Boston, MA, United States.
Barbara A DworetzkyDivision of Epilepsy and Neurology, Brigham and Women's Hospital, Boston, MA, United States.
Gaston BasletDepartment of Psychiatry, Brigham and Women's Hospital, Boston, MA, United States.
Ginger PolichDepartment of Physical Medicine and Rehabilitation, Mass General Brigham, Boston, MA, United States.
M Angela O'NealDepartment of Neurology, Brigham and Women's Hospital, Boston, MA, United States.
Claus ReinsbergerDivision of Sports Neurology and Neurosciences, Mass General Brigham Boston, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional neurological disorder (FND) is a common neurologic disorder associated with many comorbid symptoms including fatigue, pain, headache, and orthostasis. These concurrent symptoms lead patients to accumulate multiple diagnoses comorbid with FND, including fibromyalgia, chronic fatigue syndrome, postural orthostatic tachycardia syndrome, persistent post-concussive symptoms, and chronic pain. The role of physical activity and exercise has not been evaluated in FND populations, though has been studied in certain comorbid conditions. In this traditional narrative literature review, we highlight some existing literature on physical activity in FND, then look to comorbid disorders to highlight the therapeutic potential of physical activity. We then consider abnormalities in the autonomic nervous system (ANS) as a potential pathophysiological explanation for symptoms in FND and comorbid disorders and postulate how physical activity and exercise may provide benefit via autonomic regulation.

Indexed as

Autonomic nervous systemExerciseFunctional neurological disorderPhysical activityPsychogenic

Identifiers

PMID38953100
PMCPMC11215960

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.