Evidence map›Paper›PMID 38953049›Full record

ArticleResearch and practice in thrombosis and haemostasis2024

Heavy menstrual bleeding on direct factor Xa inhibitors: the MEDEA randomized clinical trial.

Eva N Hamulyák, Hanke M G Wiegers, Barbara A Hutten, Maria E de Lange, Anne Timmermans, Peter E Westerweel, Marten R Nijziel, Frederikus A Klok, Marcel M Hovens, Pieter W Kamphuisen and 3 more

Abstract read
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In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Déjà vu all over again: a recurrent flaw in anticoagulant study design.Journal of thrombosis and haemostasis : JTH · 2025
    Pooled it
  3. Article
  4. Review
  5. Article
  6. Pharmacists' Knowledge of Abnormal Uterine Bleeding in Women on Anticoagulant Therapy: A French Survey.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Eva N HamulyákDepartment of Vascular Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Hanke M G WiegersDepartment of Vascular Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Barbara A HuttenDepartment of Epidemiology and Data Science, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Maria E de LangeDepartment of Gynecology and Obstetrics, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Anne TimmermansDepartment of Gynecology and Obstetrics, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Peter E WesterweelDepartment of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
Marten R NijzielDepartment of Hematology, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Frederikus A KlokDepartment of Medicine - Thrombosis and Haemostasis, Leiden University Medical Center, Leiden, The Netherlands.
Marcel M HovensDepartment of Internal Medicine, Rijnstate Hospital, Arnhem, The Netherlands.
Pieter W KamphuisenDepartment of Vascular Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Harry R BüllerDepartment of Vascular Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Saskia MiddeldorpDepartment of Vascular Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Luuk J J ScheresDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID38953049
PMCPMC11215107

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.