Evidence map›Paper›PMID 38952949›Full record

ArticleLeukemia research reports2024

Acute myeloid leukemia with a novel

Yavuz Sahin, Jianming Pei, Don A Baldwin, Nashwa Mansoor, Lori Koslosky, Peter Abdelmessieh, Y Lynn Wang, Reza Nejati, Joseph R Testa

Abstract read
In one paragraph

Article in Leukemia research reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Identification of a novelFrontiers in oncology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yavuz SahinDepartment of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Jianming PeiDepartment of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Don A BaldwinDepartment of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Nashwa MansoorDepartment of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Lori KosloskyDepartment of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Peter AbdelmessiehDepartment of Bone Marrow Transplant and Cellular Therapies, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Y Lynn WangDepartment of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Reza NejatiDepartment of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Joseph R TestaDepartment of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy associated with various combinations of gene mutations, epigenetic abnormalities, and chromosome rearrangement-related gene fusions. Despite the significant degree of heterogeneity in its pathogenesis, many gene fusions and point mutations are recurrent in AML and have been employed in risk stratification over the last several decades. Gene fusions have long been recognized for understanding tumorigenesis and their proven roles in clinical diagnosis and targeted therapies. Advances in DNA sequencing technologies and computational biology have contributed significantly to the detection of known fusion genes as well as for the discovery of novel ones. Several recurring gene fusions in AML have been linked to prognosis, treatment response, and disease progression. In this report, we present a case with a long history of essential thrombocythemia and hallmark

Indexed as

Acute myeloid leukemiaAKAP9AKAP9::PDGFRAEssential thrombocythemiaNovel gene fusionPDGFRA

Identifiers

PMID38952949
PMCPMC11215950

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.