Evidence map›Paper›PMID 38952756›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2024

Immune-mediated pyogranulomatous panniculitis with hypercalcemia in a dog.

Oliver Waite, Anette Loeffler, Adrianna Skarbek, Virginie Fouriez-Lablee, Jennifer Irving, Sarah Tayler

Abstract readCase Reports
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Oliver WaiteDepartment of Veterinary Clinical Service (Waite, Loeffler, Skarbek, Fouriez-Lablee, Tayler) and Department of Pathobiology and Population Sciences (Irving), Royal Veterinary College, University of London, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
Anette LoefflerDepartment of Veterinary Clinical Service (Waite, Loeffler, Skarbek, Fouriez-Lablee, Tayler) and Department of Pathobiology and Population Sciences (Irving), Royal Veterinary College, University of London, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
Adrianna SkarbekDepartment of Veterinary Clinical Service (Waite, Loeffler, Skarbek, Fouriez-Lablee, Tayler) and Department of Pathobiology and Population Sciences (Irving), Royal Veterinary College, University of London, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
Virginie Fouriez-LableeDepartment of Veterinary Clinical Service (Waite, Loeffler, Skarbek, Fouriez-Lablee, Tayler) and Department of Pathobiology and Population Sciences (Irving), Royal Veterinary College, University of London, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
Jennifer IrvingDepartment of Veterinary Clinical Service (Waite, Loeffler, Skarbek, Fouriez-Lablee, Tayler) and Department of Pathobiology and Population Sciences (Irving), Royal Veterinary College, University of London, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
Sarah TaylerDepartment of Veterinary Clinical Service (Waite, Loeffler, Skarbek, Fouriez-Lablee, Tayler) and Department of Pathobiology and Population Sciences (Irving), Royal Veterinary College, University of London, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 11-year-old neutered male large crossbreed dog was presented for investigation because of a 10-day history of progressive lethargy, hyporexia, and pyrexia. Physical and dermatological examinations were unremarkable. Blood biochemical analysis identified a marked total and ionized hypercalcemia and increased C-reactive protein concentration. Bicavitary computed tomography screening for causes of the dog's clinical and biochemical abnormalities identified a diffuse panniculitis. Histopathological examination of full-thickness skin biopsies was consistent with pyogranulomatous inflammation. Extensive histochemical staining revealed no infectious etiology. Complete clinical and biochemical remissions were observed after starting immunosuppressive, followed by tapering, doses of prednisolone, supporting an immune-mediated etiology. Key clinical message: Sterile, immune-mediated pyogranulomatous inflammation should remain a differential diagnosis for hypercalcemia in dogs. Significant dermatological disease may occur without visible abnormalities.

Indexed as

Dog DiseasesHypercalcemiaPanniculitisAnimalsDogsImmunosuppressive AgentsMalePrednisoloneImmunosuppressive AgentsPrednisolone

Identifiers

PMID38952756
PMCPMC11195500

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.