ArticleClinical ophthalmology (Auckland, N.Z.)2024
Optimization of Ray-Tracing-Guided LASIK Outcomes: A Prospective Comparative Study of ZZ InnovEyes Strategy versus Automated Strategy.
Article in Clinical ophthalmology (Auckland, N.Z.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Initial Visual and Refractive Outcomes of Ray-Tracing-Guided LASIK (Wavelight Plus) Versus KLEx (SMILE Pro).Ophthalmology and therapy · 2026Article
- Ray-tracing guided versus topography-guided FS-LASIK for myopia: a comparative study of relative peripheral refraction and visual quality.BMC ophthalmology · 2026Article
- Visual Outcomes and Safety of Ray-Tracing-Guided Laser-Assisted In Situ Keratomileusis: A Systematic Review and Meta-Analysis.Ophthalmology and therapy · 2026Review
- Mechanisms of Neuroperceptual Differences Between Subjective and Objective Refraction Based on Multimodal Imaging and Neurovisual Features.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Ray-Tracing-Guided Femtosecond LASIK: Refractive Outcomes, Visual Quality and Patient Satisfaction.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Refractive outcome and visual quality of Ray-Tracing Guided LASIK: a prospective study.BMC ophthalmology · 2025Observational
- Comparison of U.S. FDA Premarket Approval Studies Between Ray Tracing-Guided LASIK with InnovEyes Sightmap Versus Topography-Guided LASIK Using Custom Ablation Treatment (T-CAT).Ophthalmology and therapy · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To evaluate the effectiveness of Zhang and Zheng's InnovEyes (ZZ InnovEyes) strategy for optimizing outcomes of ray-tracing-guided laser in situ keratomileusis (LASIK) compared to the standard automated strategy. Methods: A total of 38 patients (71 eyes) undergoing therapeutic refractive surgery at Hangzhou MSK Eye Hospital were randomly assigned to the ZZ InnovEyes and automated groups using double-masked randomization. The study assessed visual acuity, refractive outcomes, and higher-order aberrations preoperatively and at 1-day, 2-week, 1-month, and 3-month follow-ups. Statistical analysis was done with Microsoft Excel and SPSS 19.0. Results: The exposure and control groups comprised 36 and 35 eyes, respectively. The ZZ InnovEyes group demonstrated significant advantages in manifest refraction spherical equivalent (MRSE) correction compared to the automated approach group (0.13 ± 0.30 D vs 0.62 ± 0.40 D, p < 0.001), achieving 97.22% uncorrected distance visual acuity (UDVA) of 20/16 or better compared to 85.71% in the automated group at the 3-month follow-up (p = 0.08), and achieving 50.00% UDVA of 20/12.5 or better compared to 28.57% in the automated group at the 3-month follow-up (p = 0.06). Loss lines from preoperative corrected distance visual acuity to postoperative UDVA were lower in the ZZ InnovEyes group (0.00%) than the automated group (8.57%; p = 0.07). Both groups exhibited similar astigmatism corrections and higher-order aberrations. Conclusion: The ZZ InnovEyes strategy, which incorporates manifest and wavefront refraction for ray-tracing-guided LASIK, demonstrated superior MRSE correction and potential advantages in visual acuity outcomes compared to the standard automated strategy. This study highlights the need for ongoing optimization and research in refractive surgery. Clinical Trial Registration Number: ChiCTR2300078709.
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