Evidence map›Paper›PMID 38952681›Full record

ArticleiScience2024

Wnt/β-catenin signaling within multiple cell types dependent upon

Hongyan Sun, Adnan Shami Shah, Din-Chi Chiu, Alessandro Bonfini, Nicolas Buchon, Jeremy M Baskin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Hongyan SunWeill Institute for Cell & Molecular Biology, Cornell University, Ithaca, NY 14853, USA.
Adnan Shami ShahWeill Institute for Cell & Molecular Biology, Cornell University, Ithaca, NY 14853, USA.
Din-Chi ChiuWeill Institute for Cell & Molecular Biology, Cornell University, Ithaca, NY 14853, USA.
Alessandro BonfiniCornell Institute of Host Microbe Interactions and Disease, Department of Entomology, Cornell University, Ithaca, NY 14853, USA.
Nicolas BuchonCornell Institute of Host Microbe Interactions and Disease, Department of Entomology, Cornell University, Ithaca, NY 14853, USA.
Jeremy M BaskinWeill Institute for Cell & Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

Funding

Gut microbes modulate immune pathways in intestinal stem cells to influence their lineageR01AI148541 · NIAID · CORNELL UNIVERSITY · PI BUCHON, NICOLAS · 2020 to 2024
$2.9M
The role of stem-cell mediated midgut repair in the dynamics of mosquito infectionsR01AI148529 · NIAID · CORNELL UNIVERSITY · PI BUCHON, NICOLAS · 2020 to 2024
$2.6M
Phosphoinositide-Binding Proteins as Regulators of Ubiquitination and Wnt SignalingR01GM131101 · NIGMS · CORNELL UNIVERSITY · PI BASKIN, JEREMY · 2018 to 2022
$1.7M
The taste and smell of intestinal stem cells and its impact on proliferation and lifespanR21AG065733 · NIA · CORNELL UNIVERSITY · PI BUCHON, NICOLAS · 2020 to 2021
$432k
NIAID NIH HHS R01 AI148529NIAID NIH HHS R01 AI148541NIA NIH HHS R21 AG065733NIGMS NIH HHS R01 GM131101
6 · The paper itself

Abstract

The gut epithelium is subject to constant renewal, a process reliant upon intestinal stem cell (ISC) proliferation that is driven by Wnt/β-catenin signaling. Despite the importance of Wnt signaling within ISCs, the relevance of Wnt signaling within other gut cell types and the underlying mechanisms that modulate Wnt signaling in these contexts remain incompletely understood. Using challenge of the

Indexed as

Biological sciencesDevelopmental biologyNatural sciences

Identifiers

PMID38952681
PMCPMC11215309

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.